1661. Impact of Social Needs Case Management on Use of Medical and Behavioral Health Services: Secondary Analysis of a Randomized Controlled Trial.
作者: Mark D Fleming.;Crystal Guo.;Margae Knox.;Daniel M Brown.;Elizabeth A Hernandez.;Amanda L Brewster.
来源: Ann Intern Med. 2023年176卷8期1139-1141页 1662. Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults: A Guidance Statement From the American College of Physicians (Version 2).
作者: Amir Qaseem.;Curtis S Harrod.;Carolyn J Crandall.;Timothy J Wilt.; .;Ethan M Balk.;Thomas G Cooney.;J Thomas Cross.;Nick Fitterman.;Michael Maroto.;Adam J Obley.;Jeffrey Tice.;Janice E Tufte.;Tatyana Shamliyan.;Jennifer Yost.
来源: Ann Intern Med. 2023年176卷8期1092-1100页
The purpose of this updated guidance statement is to guide clinicians on screening for colorectal cancer (CRC) in asymptomatic average-risk adults. The intended audience is all clinicians. The population is asymptomatic adults at average risk for CRC.
1664. In relapsing AAV with rituximab-induced remission, maintenance rituximab vs. azathioprine reduced relapse at ≥32 mo.
Smith RM, Jones RB, Specks U, et al; RITAZAREM co-investigators. Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease: an international randomised controlled trial. Ann Rheum Dis. 2023;82:937-944. 36958796.
1666. In uncontrolled T2DM treated with a basal-bolus insulin regimen, weekly icodec was noninferior to daily glargine for HbA1c at 26 wk.
Mathieu C, Ásbjörnsdóttir B, Bajaj HS, et al. Switching to once-weekly insulin icodec versus once-daily insulin glargine U100 in individuals with basal-bolus insulin-treated type 2 diabetes (ONWARDS 4): a phase 3a, randomised, open-label, multicentre, treat-to-target, non-inferiority trial. Lancet. 2023;401:1929-1940. 37156252.
1667. Achievement of Guideline-Recommended Targets in Diabetes Care in China : A Nationwide Cross-Sectional Study.
作者: Victor W Zhong.;Dongmei Yu.;Liyun Zhao.;Yuxiang Yang.;Xiaoguang Li.;Yuge Li.;Yue Huang.;Gangqiang Ding.;Hui Wang.
来源: Ann Intern Med. 2023年176卷8期1037-1046页
Nationwide achievement of guideline-recommended diabetes care targets has not been comprehensively assessed in China.
1668. In noncritical COVID-19, therapeutic vs. prophylactic anticoagulation did not reduce a composite adverse clinical outcome at 30 d.
Stone GW, Farkouh ME, Lala A, et al; FREEDOM COVID Anticoagulation Strategy Randomized Trial Investigators. Randomized trial of anticoagulation strategies for noncritically ill patients hospitalized with COVID-19. J Am Coll Cardiol. 2023;81:1747-1762. 36889611.
1669. In DVT, oral DTIs and factor Xa inhibitors reduce major bleeding but not recurrent VTE vs. conventional anticoagulants.
Wang X, Ma Y, Hui X, et al. Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of deep vein thrombosis. Cochrane Database Syst Rev. 2023;4:CD010956. 37058421.
1670. In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level.
Harrington J, Carnicelli AP, Hua K, et al. Direct oral anticoagulants versus warfarin across the spectrum of kidney function: patient-level network meta-analyses from COMBINE AF. Circulation. 2023;147:1748-1757. 37042255.
1671. In ischemic stroke, EVT improved 90-d function more than usual care across admission SBP levels.
Samuels N, van de Graaf RA, Mulder MJHL, et al; HERMES Collaborators. Admission systolic blood pressure and effect of endovascular treatment in patients with ischaemic stroke: an individual patient data meta-analysis. Lancet Neurol. 2023;22:312-319. 36931806.
1672. In noncardiac surgery, hypotension- vs. hypertension-avoidance strategies did not differ for 30-d major vascular complications.
Marcucci M, Painter TW, Conen D, et al; POISE-3 Trial Investigators and Study Groups. Hypotension-avoidance versus hypertension-avoidance strategies in noncardiac surgery: an international randomized controlled trial. Ann Intern Med. 2023;176:605-614. 37094336.
1673. SAEM issued 4 strong recommendations (high-certainty evidence) for determining cause of acute vestibular syndrome in the ED.
Edlow JA, Carpenter C, Akhter M, et al. Guidelines for reasonable and appropriate care in the emergency department 3 (GRACE-3): acute dizziness and vertigo in the emergency department. Acad Emerg Med. 2023;30:442-486. 37166022.
1674. In adults with HF, opioids do not reduce refractory breathlessness (low-certainty evidence).
Gaertner J, Fusi-Schmidhauser T, Stock S, et al. Effect of opioids for breathlessness in heart failure: a systematic review and meta-analysis. Heart. 2023;109:1064-1071.36878671.
1675. In adults with hypertension, effects of BP-lowering drug monotherapy varied by patient.
Sundström J, Lind L, Nowrouzi S, et al. Heterogeneity in blood pressure response to 4 antihypertensive drugs: a randomized clinical trial. JAMA. 2023;329:1160-1169. 37039792.
1676. Predicting Inflammatory Arthritis in At-Risk Persons: Development of Scores for Risk Stratification.
作者: Laurence Duquenne.;Elizabeth M Hensor.;Michelle Wilson.;Leticia Garcia-Montoya.;Jacqueline L Nam.;Jianhua Wu.;Kate Harnden.;Innocent Chidi Anioke.;Andrea Di Matteo.;Rahaymin Chowdhury.;Navkiran Sidhu.;Frederique Ponchel.;Kulveer Mankia.;Paul Emery.
来源: Ann Intern Med. 2023年176卷8期1027-1036页
Inflammatory arthritis (IA) is an immune-related condition defined by the presence of clinical synovitis. Its most common form is rheumatoid arthritis.
1677. Credentialing Internal Medicine Physicians to Expand Long-Acting Reversible Contraceptive Access.
作者: Jennifer L Michener.;David A Hirsh.;Pelin Batur.;Rachel S Casas.;Vidya Gopinath.;Lydia E Pace.;Christine Prifti.;Jennifer Rusiecki.;Eleanor Bimla Schwarz.;Megha Shankar.;Mindy Sobota.;Deborah Gomez Kwolek.
来源: Ann Intern Med. 2023年176卷8期1121-1123页 1679. Association Between Age and Low-Density Lipoprotein Cholesterol Response to Statins : A Danish Nationwide Cohort Study.
作者: Giulia Corn.;Mads Melbye.;Mark A Hlatky.;Jan Wohlfahrt.;Marie Lund.
来源: Ann Intern Med. 2023年176卷8期1017-1026页
There is large patient-to-patient variability in the low-density lipoprotein cholesterol (LDL-C) response to statin treatment. The reduction in LDL-C may depend on the age of the patient treated-particularly in older adults, who have been substantially underrepresented in randomized controlled trials.
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