当前位置: 首页 >> 检索结果
1381. In hypertension, with or without orthostatic hypotension, more- vs. less-intensive BP therapy improves clinical outcomes.
Juraschek SP, Hu JR, Cluett JL, et al. Orthostatic hypotension, hypertension treatment, and cardiovascular disease: an individual participant meta-analysis. JAMA. 2023;330:1459-1471. 37847274.
1382. Biomarker risk assessment model identified high-risk patients with cancer who benefit from thromboprophylaxis.
Alexander M, Harris S, Underhill C, et al. Risk-directed ambulatory thromboprophylaxis in lung and gastrointestinal cancers: the TARGET-TP randomized clinical trial. JAMA Oncol. 2023;9:1536-1545. 37733336.
1383. In primary care, second-line IBS therapy with amitriptyline vs. placebo reduced symptoms at 6 mo.
Ford AC, Wright-Hughes A, Alderson SL, et al; ATLANTIS trialists. Amitriptyline at low-dose and titrated for irritable bowel syndrome as second-line treatment in primary care (ATLANTIS): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2023;402:1773-1785. 37858323.
1384. Reducing Care Overuse in Older Patients Using Professional Norms and Accountability : A Cluster Randomized Controlled Trial.
作者: Stephen D Persell.;Lucia C Petito.;Ji Young Lee.;Daniella Meeker.;Jason N Doctor.;Noah J Goldstein.;Craig R Fox.;Theresa A Rowe.;Jeffrey A Linder.;Ryan Chmiel.;Yaw Amofa Peprah.;Tiffany Brown.
来源: Ann Intern Med. 2024年177卷3期324-334页
Effective strategies are needed to curtail overuse that may lead to harm.
1385. Suicide Attempts After a Diagnosis of Polycystic Ovary Syndrome : A Cohort Study.
作者: Tien-Wei Hsu.;Yu-Chen Kao.;Shih-Jen Tsai.;Ya-Mei Bai.;Tung-Ping Su.;Tzeng-Ji Chen.;Chih-Sung Liang.;Mu-Hong Chen.
来源: Ann Intern Med. 2024年177卷3期335-342页
Limited evidence exists about suicide risk in persons with polycystic ovary syndrome (PCOS).
1390. Trends in Discharge Rates for Acute Pulmonary Embolism in U.S. Emergency Departments.
作者: Nathan W Watson.;Brett J Carroll.;Anna Krawisz.;Alec Schmaier.;Eric A Secemsky.
来源: Ann Intern Med. 2024年177卷2期134-143页
Outpatient management of select patients with low-risk acute pulmonary embolism (PE) has been proven to be safe and effective, yet recent evidence suggests that patients are still managed with hospitalization. Few studies have assessed contemporary real-world trends in discharge rates from U.S. emergency departments (EDs) for acute PE.
1391. The Effect of Practitioner Empathy on Patient Satisfaction : A Systematic Review of Randomized Trials.
作者: Leila Keshtkar.;Claire D Madigan.;Andy Ward.;Sarah Ahmed.;Vinay Tanna.;Ismail Rahman.;Jennifer Bostock.;Keith Nockels.;Wen Wang.;Clare L Gillies.;Jeremy Howick.
来源: Ann Intern Med. 2024年177卷2期196-209页
Practitioners who deliver enhanced empathy may improve patient satisfaction with care. Patient satisfaction is associated with positive patient outcomes ranging from medication adherence to survival.
1392. Large Language Models in Medicine: The Potentials and Pitfalls : A Narrative Review.
作者: Jesutofunmi A Omiye.;Haiwen Gui.;Shawheen J Rezaei.;James Zou.;Roxana Daneshjou.
来源: Ann Intern Med. 2024年177卷2期210-220页
Large language models (LLMs) are artificial intelligence models trained on vast text data to generate humanlike outputs. They have been applied to various tasks in health care, ranging from answering medical examination questions to generating clinical reports. With increasing institutional partnerships between companies producing LLMs and health systems, the real-world clinical application of these models is nearing realization. As these models gain traction, health care practitioners must understand what LLMs are, their development, their current and potential applications, and the associated pitfalls in a medical setting. This review, coupled with a tutorial, provides a comprehensive yet accessible overview of these areas with the aim of familiarizing health care professionals with the rapidly changing landscape of LLMs in medicine. Furthermore, the authors highlight active research areas in the field that promise to improve LLMs' usability in health care contexts.
1394. Association of Low Glomerular Filtration Rate With Adverse Outcomes at Older Age in a Large Population With Routinely Measured Cystatin C.
作者: Edouard L Fu.;Juan-Jesus Carrero.;Yingying Sang.;Marie Evans.;Junichi Ishigami.;Lesley A Inker.;Morgan E Grams.;Andrew S Levey.;Josef Coresh.;Shoshana H Ballew.
来源: Ann Intern Med. 2024年177卷3期269-279页
The commonly accepted threshold of glomerular filtration rate (GFR) to define chronic kidney disease (CKD) is less than 60 mL/min/1.73 m2. This threshold is based partly on associations between estimated GFR (eGFR) and the frequency of adverse outcomes. The association is weaker in older adults, which has created disagreement about the appropriateness of the threshold for these persons. In addition, the studies measuring these associations included relatively few outcomes and estimated GFR on the basis of creatinine level (eGFRcr), which may be less accurate in older adults.
1395. A New Equilibrium for Telemedicine: Prevalence of In-Person, Video-Based, and Telephone-Based Care in the Veterans Health Administration, 2019-2023.
作者: Jacqueline M Ferguson.;Charlie M Wray.;James Van Campen.;Donna M Zulman.
来源: Ann Intern Med. 2024年177卷2期262-264页 1396. Health Care Contact Days Among Older Adults in Traditional Medicare : A Cross-Sectional Study.
作者: Ishani Ganguli.;Emma D Chant.;E John Orav.;Ateev Mehrotra.;Christine S Ritchie.
来源: Ann Intern Med. 2024年177卷2期125-133页
Days spent obtaining health care outside the home can represent not only access to needed care but also substantial time, effort, and cost, especially for older adults and their care partners. Yet, these "health care contact days" have not been characterized.
1398. Gene Therapy Versus Common Care for Eligible Individuals With Sickle Cell Disease in the United States : A Cost-Effectiveness Analysis.
作者: Anirban Basu.;Aaron N Winn.;Kate M Johnson.;Boshen Jiao.;Beth Devine.;Jane S Hankins.;Staci D Arnold.;M A Bender.;Scott D Ramsey.
来源: Ann Intern Med. 2024年177卷2期155-164页
Sickle cell disease (SCD) and its complications contribute to high rates of morbidity and early mortality and high cost in the United States and African heritage community.
|