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61. Cumulative defined daily doses enables objective assessment of treatment intensity and outcome prediction in immunoglobulin G4-related disease and its subtypes.
作者: Hung-Cheng Tsai.;Hsin-Yu Lu.;Chang-Youh Tsai.;Hsien-Tzung Liao.;Ming-Han Chen.;I-Lin Tsai.;Li-Ling Wu.;Ying-Ying Yang.
来源: Rheumatology (Oxford). 2026年
Immunoglobulin G4-related disease (IgG4-RD) is a chronic fibroinflammatory disorder with heterogeneous clinical behavior. Although glucocorticoids remain the mainstay of treatment, relapse and fibrosis are common. This study investigated predictors of relapse and mortality, integrating disease subtype and cumulative drug exposure using the defined daily dose (DDD) framework.
62. Coping with rheumatic stressors in longstanding axial spondyloarthritis: association with patient and disease characteristics.
作者: Marc van Essen.;Dafne Capelusnik.;Désirée van der Heijde.;Robert B M Landewé.;Wim van Lankveld.;Astrid van Tubergen.;Sofia Ramiro.;Annelies Boonen.
来源: Rheumatology (Oxford). 2026年
Coping strategies have been shown to influence health outcomes of persons with axSpA. This study explores which stable and variable factors are associated with coping and whether coping strategies change over time.
63. Certolizumab pegol, abatacept, tocilizumab or active conventional therapy in early rheumatoid arthritis: 48-week patient-reported outcomes from the NORD-STAR trial.
作者: Jon Lampa.;Dan Nordström.;Ronald van Vollenhoven.;Merete Lund Hetland.;Espen A Haavardsholm.;Mikkel Østergaard.;Anna Rudin.;Marte S Heiberg.;Michael Nurmohamed.;Bjorn Gudbjornsson.;Kristina Lend.;Kim Hørslev-Petersen.;Tuulikki Sokka-Isler.;Gerður Gröndal.;Simon Krabbe.;Joakim Lindqvist.;Inger Gjertsson.;Daniel Glinatsi.;Meliha Kapetanovic.;Cidem Gentline.;Anna-Birgitte Aga.;Heikki Relas.;Tove Lorenzen.;Giovanni Cagnotto.;Johan Back.;Oliver Hendricks.;Bas Dijkshoorn.;Kajsa Öberg.;Maud-Kristine Ljoså.;Eli Brodin.;Hanne Merete Lindegaard.;Annika Söderbergh.;Milad Rizk.;Alf Kastbom.;Per Larsson.;Line Uhrenholt.;Søren A Just.;David J Stevens.;Trine B Laurberg.;Gunnstein Bakland.;Inge C Olsen.;Joe Sexton.;Till Uhlig.; .
来源: Lancet Rheumatol. 2026年8卷4期e285-e294页
Pain, fatigue, and impaired health-related quality of life are common manifestations of rheumatoid arthritis. The aim of this study was to compare the effects of active conventional treatment with three different biological disease-modifying antirheumatic drugs (DMARDs) on patient-reported outcomes after 48 weeks, in patients with early rheumatoid arthritis using data from the NORD-STAR trial.
64. Development of patient-initiated follow-up resources for UK rheumatology departments: a co-design study with patient and clinician collaboration.
作者: Alice E Jennings.;Ailsa Bosworth.;Mel Brooke.;Joe Eddison.;James Galloway.;Mark G Perry.;Helen Lall.;Rob Law.;Laura C Coates.;Emma Dures.
来源: Lancet Rheumatol. 2026年8卷4期e265-e273页
Patient-initiated follow-up (PIFU) is designed to give patients more control over their follow-up care in rheumatology and relies on patients coming forward to schedule appointments and understand how and when to contact their rheumatology team. Additionally, rheumatology teams need to establish suitable criteria and have systems in place to support PIFU. Resources to inform patients with rheumatic disease about PIFU or to support its implementation in rheumatology clinics is scarce. The aim of this study was to co-design resources with patients and clinicians to support the implementation of PIFU across the UK.
65. LupusGPT: an AI-driven information model for patients with systemic lupus erythematosus.
作者: Zoe Karakikla-Mitsakou.;Alain Cornet.;Jeanette Andersen.;Sarah Dyball.;Cristiana Sieiro Santos.;Daniel Guimarães de Oliveira.;Laurent Arnaud.
来源: Lancet Rheumatol. 2026年8卷4期e238-e242页 70. Application of a novel Musculoskeletal Ultrasound Sum Score (MUSS) in the follow-up of patients with juvenile idiopathic arthritis.
The objective of this study was to evaluate the novel Musculoskeletal Ultrasound Sum Score (MUSS) as a longitudinal marker of disease activity (DA) in patients with JIA within a treat-to-target management approach.
71. Urological manifestations in familial mediterranean fever excluding renal amyloidosis: a systematic review.
作者: Aziz Kutay Ozcan.;Baris Karaoglan.;Berkay Gundogdu.;Cansu Sahin.;Muhammed Fatih Simsekoglu.;Serdal Ugurlu.
来源: Rheumatology (Oxford). 2026年
To systematically review the spectrum of urological manifestations and fertility outcomes reported in FMF patients, excluding renal amyloidosis-related involvement.
72. Soluble SIGLEC1 as a biomarker of disease activity in idiopathic inflammatory myopathies.
作者: Nathan Barreth.;Valérie Leclair.;Marie Hudson.;Sasha Bernatsky.;Eugene Krustev.;Cristina Moran Toro.;Yvan St Pierre.;Ashley Clarke.;Paul J A Sciore.;Mark Tarnopolsky.;Marvin J Fritzler.;May Y Choi.; .
来源: Rheumatology (Oxford). 2026年
To investigate soluble circulating sialic acid-binding Ig-like lectin 1 (scSIGLEC1), a surrogate biomarker for type I interferon, as a novel biomarker for idiopathic inflammatory myopathies (IIM) disease activity.
73. A treat-to-target strategy versus symptom-driven management of gout in the Netherlands (GO TEST Overture): a multicentre, open-label, pragmatic, superiority, randomised controlled trial.
作者: Anusha Moses.;Martijn A H Oude Voshaar.;Eva H van Geel.;Lydia Schipper.;Iris Rose Peeters.;Reinhard Bos.;Caroline van Durme.;Mart A F J van de Laar.;Tim L Jansen.
来源: Lancet Rheumatol. 2026年
A treat-to-target approach is recommended for gout management, which involves titrating urate-lowering therapy to reach a serum urate target of less than 0·36 mmol/L, but evidence from pragmatic, head-to-head trials comparing a treat-to-target strategy with a symptom-driven approach is scarce. We aimed to address this gap by comparing these two approaches in patients with gout.
75. Rheumatologist assessment in established polymyalgia rheumatica.
作者: Elisabeth Lindrup Nielsen.;Agnete Overgaard Donskov.;Christoffer Søvsø Våben.;Andreas Wiggers Nielsen.;Line Lier Frølund.;Ib Tønder Hansen.;Line Thorndal Moll.;Berit Dalsgaard Nielsen.;Christoffer Mørk.;Ellen-Margrethe Hauge.;Kresten Krarup Keller.
来源: Rheumatology (Oxford). 2026年65卷4期
Patients with established polymyalgia rheumatica (PMR) are often referred from general practitioners (GPs) to rheumatologists. This single-centre cohort study examined the frequency, indications and diagnostic outcomes of patients with established PMR referred to a rheumatology outpatient clinic after initial diagnosis by GPs or rheumatologists in a hospital outpatient setting.
76. Central pain sensitivity is associated with changes in fatigue in RA: data from the CAP-RA study.
作者: Vasileios Georgopoulos.;Stephanie L Smith.;David A Walsh.;Daniel F McWilliams.
来源: Rheumatology (Oxford). 2026年65卷4期
This observational study examined whether central pain sensitivity is associated with fatigue in RA and whether such associations are explained by pain severity or inflammation.
77. Sex-based differences in bDMARD initiation and persistence in spondyloarthritis: a 17-year follow-up study from the REGISPON-3 registry.
作者: Diana Maria Margareta Moldovan.;Lourdes Ladehesa-Pineda.;María Ángeles Puche-Larrubia.;María Carmen Ábalos-Aguilera.;Desirée Ruiz-Vilchez.;Raquel Ena María Granados.;Carlos M Collantes-Sánchez.;Alejandro Escudero-Contreras.; .;Eduardo Collantes-Estévez.;Clementina López-Medina.
来源: Rheumatology (Oxford). 2026年
This study examines sex differences in the initiation and retention rate of biological disease-modifying antirheumatic drugs (bDMARDs) among patients with spondyloarthritis (SpA) over a 17-year follow-up period, and identifies sex-specific predictors of these treatment outcomes.
78. Exploring sleep health and circadian rhythm disruption in Sjögren's disease: an accelerometric and self-reported cross-sectional study.
作者: Caterina Di Pede.;Alessandro Colitta.;Simone Bruno.;Paolo Frumento.;Michelangelo Maestri Tassoni.;Giovanni Fulvio.;Gaetano La Rocca.;Enrica Bonanni.;Marta Mosca.;Rosaria Talarico.;Chiara Baldini.;Ugo Faraguna.
来源: Rheumatology (Oxford). 2026年65卷4期
In a cross-sectional study, we aimed at characterizing possible impairments in sleep health and rest-activity parameters between patients with Sjögren's Disease (SjD) and healthy controls (HCs). Furthermore, we explored possible predictors of such disturbances in the SjD group.
79. Treatment satisfaction, disease severity, and health-care use in patients with axial spondyloarthritis in the United States and Europe.
作者: Elena Nikiphorou.;Alexis Ogdie.;Dan Twigg.;Emily Quiñones.;You-Li Ling.;Joseph C Cappelleri.;Lidia Sanchez-Riera.;Karim R Masri.;Megan Hughes.;Nicola Massey.
来源: Rheumatology (Oxford). 2026年65卷3期
The heterogeneous presentation of axial SpA (axSpA) complicates diagnosis and treatment decisions. This study compared patient symptoms, health-care resource utilization, and physician-patient alignment on disease severity and treatment satisfaction between the USA and five European countries (5EU).
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