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62. Expert Consensus Framework for Standardizing Lung Ultrasound Training for Neonatologists issued by ESPNIC Neonatal Critical Care Section and Point-of-care Ultrasound Working Group.
作者: Yogen Singh.;Manuel Sanchez Luna.;Belinda Chan.;Almudena Alonso-Ojembarrena.;Nadya Yousef.;Mahmoud Montasser.;Virginie Meau Petit.;Iuri Corsini.;Pradeep Suryawanshi.;Alok Sharma.;Anna Milan.;Lukas Aichhorn.;Simona Vladareanu.;Francesco Raimondi.;Daniele De Luca.
来源: Chest. 2026年
To provide an expert consensus framework for standardizing lung ultrasound training for neonatologists.
65. Association of sleep-related hypoxemia with survival in patients with non-small cell lung cancer - the NEOSAS-GFPC study group.
作者: Grégoire Justeau.;Laurent Greillier.;Florent Vinas.;Lionel Falchero.;Olivier Bylicki.;Marie Bernardi.;Francis Martin.;Isabelle Simon.;Didier Debieuvre.;Chrystèle Locher.;Acya Bizieux-Thaminy.;Virginie Levrat.;Stéphanie Fry.;Camille Guguen.;Frédéric Goutorbe.;Philippe Masson.;Franck Soyez.;Christos Chouaid.;Patrick Saulnier.;Frédéric Gagnadoux.
来源: Chest. 2026年
Obstructive sleep apnea (OSA) and its hypoxia-related consequences are associated with an increased lung cancer risk.
66. Effects of a Novel Dual Phosphodiesterase 3 and 4 Inhibitor TQC3721 in Patients With COPD in China (PACER-II): A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.
作者: Li-Xiu He.;Ling Yang.;Zu-Ke Xiao.;Rong Qiu.;Fa-Ming Yu.;Li-Qin Wu.;Wei-Hua Zhang.;Xun-Chao Liu.;Ling-Feng Min.;Xiu-Qin Ma.;Jian-Zhong Jiang.;Bo Yuan.;Ran-Ran Dai.;Dong Liu.;Xiao-Hua Li.;Tao Wang.;Jie Cao.;Xiao-Bin Luo.;Xiao-Ju Liu.;Chao Chen.;Wei-Guo Li.;Ding Yu.;Zhu Luo.;Wei-Min Li.; .
来源: Chest. 2026年
Dual phosphodiesterase (PDE) 3 and 4 inhibitors have emerged as a novel therapeutic strategy for COPD, but their applicability remains limited to specific treatment contexts. To our knowledge, TQC3721 is a novel inhaled dual PDE3 and PDE4 inhibitor with synergistic bronchodilator and antiinflammatory effects.
67. Real-World Use of Consumer Sleep Devices: A Rapid Review.
As awareness of sleep's role in health grows, consumer sleep technologies (CSTs) have gained wide use among both researchers and the public. These devices offer continuous, noninvasive sleep tracking in real-world environments. However, understanding their accuracy compared with that of polysomnography (PSG), the gold standard in sleep measurement, remains limited, particularly in free-living settings and clinical populations. Assessing CST performance and usability in these contexts is essential for guiding future adoption.
68. Prophylactic haemostatic treatment to control iatrogenic bleeding during endobronchial biopsy (PROTECT study): a multicentre, randomised, single-blind, placebo-controlled study.
作者: Bei Li.;Li He.;Wei Wu.;Min Ji.;Wen Zhang.;Lina Wang.;Tanushree Kochar.;Fang Yue.;Aijun Zhang.;Yijun Ge.;Xiaoyan Jin.;Yan Zhang.;Hongying Ma.;Qunli Ding.;Fei Tang.;Chao Cao.
来源: Chest. 2026年
Iatrogenic bleeding related to endobronchial biopsy could be catastrophic and might lead to fatal outcomes. Although some guidelines and studies recommended the prophylactic use of haemostatic agents, there was still insufficient evidence from clinical studies.
69. The Minimal Important Difference in N-Terminal Pro-Brain Natriuretic Peptide in Pulmonary Hypertension.
作者: Matthew R Lammi.;Sarah L Khan.;Youlan Rao.;Wei Zhao.;Aparna Balasubramanian.;Stephen C Mathai.
来源: Chest. 2026年
N-terminal pro-brain natriuretic peptide (NT-proBNP) is a commonly used biomarker of right heart function in patients with pulmonary hypertension.
70. Antimicrobial Treatment of Mild Mycobacterium avium Complex-Pulmonary Disease Predicted to Increase Survival and Quality Adjusted Life Years: A Microsimulation Decision Analysis Model.
作者: Omri A Arbiv.;Gemma Postill.;Yunjoo Im.;Byung Woo Jhun.;Petros Pechlivanoglou.;Sarah K Brode.;Ahmed M Bayoumi.;Theodore K Marras.
来源: Chest. 2026年
Mycobacterium avium complex-pulmonary disease (MAC-PD) can lead to chronic lung disease, which can necessitate intensive antimicrobial therapy. In patients with mild MAC-PD, there is uncertainty in whether guideline-based antimicrobial treatment should be used as compared to watchful waiting.
71. MMP12 Improves the Differentiation of Idiopathic Pulmonary Fibrosis and Fibrotic Hypersensitivity Pneumonitis and Associates with Antigen Response Pathways.
作者: Sam B Konkol.;Yong Huang.;Shwu-Fan Ma.;Stephen Humphries.;David Lynch.;Tessy Paul.;Numaan Malik.;Emma Strickland.;Hannah Mannem.;Justin Oldham.;Adegunsoye Ayodeji.;Chad Newton.;Andrea Oh.;Fernando Martinez.;Anne I Sperling.;John Kim.;Imre Noth.
来源: Chest. 2026年 72. OSA is associated with enhanced coronary collateral circulation and reduced myocardial injury during acute coronary syndromes.
作者: Krish Dodani.;Albina Aldomà.;Adriano Targa.;Manuel Sánchez-de-la-Torre.;Alicia Sánchez-de-la-Torre.;Lucía Pinilla.;Jorge Abad.;Olga Mínguez.;Lydia Pascual.;Dolores Martínez.;Rafaela Vaca.;Ivan Juez-Garcia.;Ferran Barbé.;Ivan Benitez.
来源: Chest. 2026年
Some evidence suggests that obstructive sleep apnea (OSA) may attenuate myocardial injury and reduce infarct severity during acute coronary syndromes (ACS), potentially through stimulation of coronary collateral circulation (CCC). However, the relationship between OSA and collateral development, and their combined impact on ACS event severity, remains unclear.
73. Clinical sampling challenges in diagnosing severe respiratory viral infections.
作者: Antonio Piralla.;Cristina Russo.;Stefania Ranno.;Carla Acciarri.;Stefano Menzo.;Sara Uceda Renteria.;Annapaola Callegaro.;Maria Vittoria Francescon.;Elisa Vian.;Elisa Masi.;Elisabetta Pagani.;Giulia Piccirilli.;Tiziana Lazzarotto.;Alessandra Pierangeli.;Guido Antonelli.;Federica Novazzi.;Nicasio Mancini.;Fausto Baldanti.;Elena Pariani.; .
来源: Chest. 2026年
Respiratory viruses are a primary cause of pneumonia in both children and adults, particularly in cases of severe acute respiratory infection (SARI) requiring hospitalization. Although molecular diagnostic technologies have clearly enhanced detection capacity, the selection process of the sampling site substantially influences diagnostic accuracy.
74. Clinical and cost-effectiveness of pulmonary rehabilitation for people with post-tuberculosis lung disease in Uganda: a randomised controlled trial.
作者: Winceslaus Katagira.;Mark W Orme.;Richard Kasiita.;Jesse A Matheson.;Matthew Richardson.;Andy Barton.;Jalia Nanyonga.;Michael C Steiner.;Bruce Kirenga.;Sally J Singh.
来源: Chest. 2026年
Background Post-tuberculosis lung disease (PTLD) causes significant disability in TB survivors. Pulmonary rehabilitation (PR) may offer effective disease management but lacks high-quality evidence in this underrepresented population.
75. Win Ratio Analysis to Clarify Clinical Benefits: A Post Hoc Analysis of Phase 3 BOREAS and NOTUS.
作者: Sanjay Ramakrishnan.;Nayia Petousi.;Jessica Bon.;Ian D Pavord.;Surya P Bhatt.;Klaus F Rabe.;Wenying Deng.;Changming Xia.;Jigna Heble.;Mena Soliman.;Simon Couillard.
来源: Chest. 2026年 76. Evaluating the Association Between Patient Priorities and ICU Care Delivery in Adults Receiving Mechanical Ventilation.
作者: Kara A Donovan.;Madison Polley.;Geralyn Palmer.;Bret M Hanlon.;Lily N Stalter.;Helen K Donnelly.;Richard G Wunderink.;Catherine A Gao.;Jacqueline M Kruser.; .
来源: Chest. 2026年
Understanding how intensive care unit (ICU) treatments align with a patient's priorities is crucial to evaluating and improving critical care. Yet, measuring this alignment is challenging because patient priorities evolve over time and are not systematically documented in electronic health records (EHR).
77. Association of High Cardiovascular Disease Risk Obstructive Sleep Apnea with Incident Atrial Fibrillation: the Multi-Ethnic Study of Atherosclerosis.
作者: Jing Xu.;Younghoon Kwon.;Neda Esmaeili.;Scott A Sands.;Mohammadreza Hajipour.;Daniel Vena.;Susan R Heckbert.;Elsayed Z Soliman.;Andrew Wellman.;Erin D Michos.;Daniel J Gottlieb.;Susan Redline.;Ali Azarbarzin.
来源: Chest. 2026年
Obstructive sleep apnea (OSA) is associated with atrial fibrillation (AF), but this association varies by population and definitions of OSA and AF.
78. Demographic and physiologic differences between fibrotic and non-fibrotic CT subtypes of sarcoidosis.
作者: Ruchi Yadav.;Wren L Lippitt.;Kum Ju Chae.;Jared Rieck.;Nichole E Carlson.;Shu-Yi Liao.;Margaret M Mroz.;Briana Barkes.;Stephen M Humphries.;Andrea Oh.;Hye Jeon Hwang.;Katherine Parker.;Andrea I Fuentealba.;Thomas McLaren.;Cristina Marrocchio.;Tasha E Fingerlin.;Daniel A Culver.;David A Lynch.;Lisa A Maier.
来源: Chest. 2026年
One approach to categorizing patients using chest computed tomography (CT) imaging manifestations of pulmonary sarcoidosis is into three classifications: fibrotic, non-fibrotic, or no parenchymal abnormality. We aimed to evaluate the relationships between these imaging subtypes and demographic and physiologic variables in a large group of sarcoidosis patients with chest CT.
79. Understanding Pulmonary Fibrosis in Pediatric Interstitial Lung Disease: A Comprehensive Analysis.
作者: Handan Kekec.;Ayse Tana Aslan.;Ismail Akdulum.;Tugba Sismanlar Eyuboglu.;Ozge Ulgen.;Yasemin Mocan.;Sinem Can Oksay.;Deniz Dogru.;Ugur Ozcelık.;Meltem Akgul Erdal.;Figen Gulen.;Bahar Girgin Dindar.;Ece Ocak.;Fatma Nur Ayman.;Bahar Ece Tokdemir.;Gökçen Unal.;Fazılcan Zirek.;Esin Gizem Olgun.;Merve Nur Tekin.;Aysen Bingol.;Abdurrahman Erdem Basaran.;Betül Bankoglu Parlak.;Bülent Karadağ.;Merve Selcuk Balcı.;Almala Pınar Ergenekon.;Mehmet Kose.;Ali Ersoy.;Celebi Yıldırım.;Goksen Dilşa Tugcu.;Beste Ozsezen.;Zeynep Seda Uyan.;Ayşe Kalyoncu Ucar.;Tuğba Ramaslı Gursoy.;Mahir Serbes.;Sedat Oktem.;Pelin Asfuroglu.;Melih Hangul.;Halime Nayır Buyuksahın.;Mina Hızal.;Gokcen Kartal Ozturk.;Ayşe Ayzıt Kılınc Sakallı.;Ebru Yalcın.;Saniye Girit.;Sevgi Pekcan.;Nagehan Emiralioglu.;Nazan Cobanoglu.;Güzin Cinel.;Yasemin Gökdemir.;Diclehan Orhan.;Ahmet Cevdet Ceylan.;Berna Oguz.;Nural Kiper.
来源: Chest. 2026年
Childhood interstitial lung diseases (chILDs) encompass a wide range of rare, chronic respiratory disorders, with pulmonary fibrosis (PF) being the clinical entity closely associated with mortality and morbidity.
80. The Impact of Weight Loss on the Physiological Endotypes Associated With OSA.
作者: Caroline J Beatty.;Ai-Ming Wong.;Shane A Landry.;Luke D J Thomson.;Jinny Collet.;Veronica Odeke.;Simon A Joosten.;Julie Playfair.;Atul Malhotra.;Kirk Kee.;Matthew T Naughton.;Kate Sutherland.;Peter A Cistulli.;Sanjay R Patel.;Wendy A Brown.;Garun S Hamilton.;Bradley A Edwards.
来源: Chest. 2026年
Weight loss improves upper airway collapsibility in people with OSA. However, it is unclear how weight loss affects the other physiological traits (ie, endotypes) associated with OSA (loop gain, arousal threshold, and muscle compensation).
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