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6923. Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline Update From the American College of Physicians.
作者: Amir Qaseem.;Michael J Barry.;Linda L Humphrey.;Mary Ann Forciea.; .;Nick Fitterman.;Carrie Horwitch.;Devan Kansagara.;Robert M McLean.;Timothy J Wilt.
来源: Ann Intern Med. 2017年166卷4期279-290页
The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on oral pharmacologic treatment of type 2 diabetes in adults. This guideline serves as an update to the 2012 ACP guideline on the same topic. This guideline is endorsed by the American Academy of Family Physicians.
6926. Firearm Acquisition Without Background Checks: Results of a National Survey.
In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist.
6927. Clinical Outcomes of Metformin Use in Populations With Chronic Kidney Disease, Congestive Heart Failure, or Chronic Liver Disease: A Systematic Review.
作者: Matthew J Crowley.;Clarissa J Diamantidis.;Jennifer R McDuffie.;C Blake Cameron.;John W Stanifer.;Clare K Mock.;Xianwei Wang.;Shuang Tang.;Avishek Nagi.;Andrzej S Kosinski.;John W Williams.
来源: Ann Intern Med. 2017年166卷3期191-200页
Recent changes to the U.S. Food and Drug Administration boxed warning for metformin will increase its use in persons with historical contraindications or precautions. Prescribers must understand the clinical outcomes of metformin use in these populations.
6928. Detecting Heterogeneous Treatment Effects to Guide Personalized Blood Pressure Treatment: A Modeling Study of Randomized Clinical Trials.
Two recent randomized trials produced discordant results when testing the benefits and harms of treatment to reduce blood pressure (BP) in patients with cardiovascular disease (CVD).
6933. Aortic Stenosis.
作者: Faisal G Bakaeen.;Todd K Rosengart.;Blase A Carabello.
来源: Ann Intern Med. 2017年166卷1期ITC1-ITC16页
This issue provides a clinical overview of aortic stenosis, focusing on screening, diagnosis, treatment, and practice improvement. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.
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