当前位置: 首页 >> 检索结果
6821. High yield of bronchoscopic transparenchymal nodule access real-time image-guided sampling in a novel model of small pulmonary nodules in canines.
作者: Daniel H Sterman.;Thomas Keast.;Lav Rai.;Jason Gibbs.;Henky Wibowo.;Jeff Draper.;Felix J Herth.;Gerard A Silvestri.
来源: Chest. 2015年147卷3期700-707页
Bronchoscopic transparenchymal nodule access (BTPNA) is a novel approach to accessing pulmonary nodules. This real-time, image-guided approach was evaluated for safety, accuracy, and yield in the healthy canine model.
6822. Change of junctions between stations 10 and 4 in the new International Association for the Study of Lung Cancer Lymph Node Map: a validation study from a single, tertiary referral hospital experience.
作者: Sunyoung Lee.;Ho Yun Lee.;Kyung Soo Lee.;Miyeon Yie.;Jaeil Zo.;Young Mog Shim.;Joungho Han.;Joong Hyun Ahn.
来源: Chest. 2015年147卷5期1299-1306页
Some tumors previously staged as N2 disease, using the Mountain-Dresler/American Thoracic Society (MD-ATS) map are staged as N1 per the new International Association for the Study of Lung Cancer (IASLC) lymph node (LN) map. We aimed to evaluate the effectiveness of the IASLC LN map in stratifying prognosis in patients with non-small cell lung cancer (NSCLC) and LN metastasis in nodal stations 4 or 10.
6823. Single-dose etomidate does not increase mortality in patients with sepsis: a systematic review and meta-analysis of randomized controlled trials and observational studies.
The effect of single-dose etomidate on mortality in patients with sepsis remains controversial. We systematically reviewed the literature to investigate whether a single dose of etomidate for rapid sequence intubation increased mortality in patients with sepsis.
6824. Optimal duration of anti-TB treatment in patients with diabetes: nine or six months?
作者: Jann-Yuan Wang.;Ming-Chia Lee.;Chin-Chung Shu.;Chih-Hsin Lee.;Li-Na Lee.;Kun-Mao Chao.;Feng-Yee Chang.
来源: Chest. 2015年147卷2期520-528页
Diabetes mellitus (DM) increases the risk of TB recurrence. This study investigated whether 9-month anti-TB treatment is associated with a lower risk of TB recurrence within 2 years after complete treatment than 6-month treatment in patients with DM with an emphasis on the impact of directly observed therapy, short course (DOTs).
6825. Derivation and validation of a CT scan scoring system for discriminating malignant from benign pleural effusions.
作者: José M Porcel.;Marina Pardina.;Silvia Bielsa.;Antonio González.;Richard W Light.
来源: Chest. 2015年147卷2期513-519页
Chest CT scanning has become an integral part of the workup for undiagnosed pleural effusions. We aimed to develop a CT scan-based scoring system for differentiating between benign and malignant pleural effusions.
6826. The association of direct thrombin inhibitor anticoagulants with cardiac thromboses.
Direct thrombin inhibitor (anti-factor IIa) anticoagulants, now established for treatment and prevention of cardiac thromboembolism and VTE, have been repeatedly associated with a significantly increased frequency of thrombosis on abnormal cardiac endothelium when compared head-to-head with indirectly acting therapeutic anticoagulants in studies of sufficient patient number and duration. Although there is uncertainty as to the mechanism, the weight of evidence as a class effect warrants prescribing effective anticoagulants other than direct thrombin inhibitors.
6827. Secular changes in relative leg length confound height-based spirometric reference values.
作者: Philip H Quanjer.;Masaru Kubota.;Hirosuke Kobayashi.;Hisamitsu Omori.;Koichiro Tatsumi.;Minoru Kanazawa.;Sanja Stanojevic.;Janet Stocks.;Tim J Cole.
来源: Chest. 2015年147卷3期792-797页
Most but not all data from different ethnic groups fit the Global Lung Function Initiative (GLI) spirometric reference model. This study investigates to what extent discrepancies are caused by secular changes in body proportions.
6828. Platelet count mediates the contribution of a genetic variant in LRRC16A to ARDS risk.
作者: Yongyue Wei.;Zhaoxi Wang.;Li Su.;Feng Chen.;Paula Tejera.;Ednan K Bajwa.;Mark M Wurfel.;Xihong Lin.;David C Christiani.
来源: Chest. 2015年147卷3期607-617页
Platelets are believed to be critical in pulmonary-origin ARDS as mediators of endothelial damage through their interactions with fibrinogen and multiple signal transduction pathways. A prior meta-analysis identified five loci for platelet count (PLT): BAD, LRRC16A, CD36, JMJD1C, and SLMO2. This study aims to validate the quantitative trait loci (QTLs) of PLT within BAD, LRRC16A, CD36, JMJD1C, and SLMO2 among critically ill patients and to investigate the associations of these QTLs with ARDS risk that may be mediated through PLT.
6829. Endosonography for mediastinal nodal staging of clinical N1 non-small cell lung cancer: a prospective multicenter study.
作者: Christophe Dooms.;Kurt G Tournoy.;Olga Schuurbiers.;Herbert Decaluwe.;Frédéric De Ryck.;Ad Verhagen.;Roel Beelen.;Erik van der Heijden.;Paul De Leyn.
来源: Chest. 2015年147卷1期209-215页
Patients with clinical N1 (cN1) lung cancer based on imaging are at risk for malignant mediastinal nodal involvement (N2 disease). Endosonography with a needle technique is suggested over surgical staging as a best first test for preoperative invasive mediastinal staging. The addition of a confirmatory mediastinoscopy seems questionable in patients with a normal mediastinum on imaging. This prospective multicenter trial investigated the sensitivity of preoperative linear endosonography and mediastinoscopy for mediastinal nodal staging of cN1 lung cancer.
6830. Validation of the GAP score in Korean patients with idiopathic pulmonary fibrosis.
作者: Eun Sun Kim.;Sun Mi Choi.;Jinwoo Lee.;Young Sik Park.;Chang-Hoon Lee.;Jae-Joon Yim.;Chul-Gyu Yoo.;Young Whan Kim.;Sung Koo Han.;Sang-Min Lee.
来源: Chest. 2015年147卷2期430-437页
No study has determined whether the risk of mortality predicted by the GAP (gender, age, and physiologic variables) model matches the observed mortality from idiopathic pulmonary fibrosis (IPF) in non-Western populations. We evaluated the clinical course of IPF and validated the GAP model in Korean patients with IPF.
6831. Direct oral anticoagulants in patients with VTE and cancer: a systematic review and meta-analysis.
作者: Maria Cristina Vedovati.;Federico Germini.;Giancarlo Agnelli.;Cecilia Becattini.
来源: Chest. 2015年147卷2期475-483页
Direct oral anticoagulants (DOAs) have been shown to be as effective and at least as safe as conventional anticoagulation for the prevention of recurrences in patients with VTE. Whether this is the case in patients with cancer-associated VTE remains undefined.
6832. Interstitial pneumonia related to undifferentiated connective tissue disease: pathologic pattern and prognosis.
作者: Ho-Cheol Kim.;Wonjun Ji.;Mi Young Kim.;Thomas V Colby.;Se Jin Jang.;Chang-Keun Lee.;Seung Bong Han.;Dong Soon Kim.
来源: Chest. 2015年147卷1期165-172页
Undifferentiated connective tissue disease (UCTD) involves conditions characterized by both having symptoms of connective tissue disease (CTD) and autoantibodies but not fulfilling the criteria of a specific CTD. The frequency or prognosis of the usual interstitial pneumonia (UIP) pattern in UCTD is unknown, which may be confused with idiopathic pulmonary fibrosis (IPF). This study aimed to investigate the frequency of the UIP pattern in interstitial pneumonia related to UCTD and compare its prognosis with that of IPF and UCTD-nonspecific interstitial pneumonia (UCTD-NSIP).
6833. Echocardiographic assessment of estimated right atrial pressure and size predicts mortality in pulmonary arterial hypertension.
作者: Christopher Austin.;Khadija Alassas.;Charles Burger.;Robert Safford.;Ricardo Pagan.;Katherine Duello.;Preetham Kumar.;Tonya Zeiger.;Brian Shapiro.
来源: Chest. 2015年147卷1期198-208页
Elevated mean right atrial pressure (RAP) measured by cardiac catheterization is an independent risk factor for mortality. Prior studies have demonstrated a modest correlation with invasive and noninvasive echocardiographic RAP, but the prognostic impact of estimated right atrial pressure (eRAP) has not been previously evaluated in patients with pulmonary arterial hypertension (PAH).
6834. A scoping review of patient discharge from intensive care: opportunities and tools to improve care.
作者: Henry T Stelfox.;Dan Lane.;Jamie M Boyd.;Simon Taylor.;Laure Perrier.;Sharon Straus.;David Zygun.;Danny J Zuege.
来源: Chest. 2015年147卷2期317-327页
We conducted a scoping review to systematically review the literature reporting patient discharge from ICUs, identify facilitators and barriers to high-quality care, and describe tools developed to improve care.
6835. Racial difference in sarcoidosis mortality in the United States.
作者: Mehdi Mirsaeidi.;Roberto F Machado.;Dean Schraufnagel.;Nadera J Sweiss.;Robert P Baughman.
来源: Chest. 2015年147卷2期438-449页
The clinical presentation and outcome of sarcoidosis varies by race. However, the race difference in mortality outcome remains largely unknown.
6836. Sex and acetazolamide effects on chemoreflex and periodic breathing during sleep at altitude.
作者: Sergio Caravita.;Andrea Faini.;Carolina Lombardi.;Mariaconsuelo Valentini.;Francesca Gregorini.;Jessica Rossi.;Paolo Meriggi.;Marco Di Rienzo.;Grzegorz Bilo.;Piergiuseppe Agostoni.;Gianfranco Parati.
来源: Chest. 2015年147卷1期120-131页
Nocturnal periodic breathing occurs more frequently in men than in women with various clinical and pathophysiologic conditions. The mechanisms accounting for this sex-related difference are not completely understood. Acetazolamide effectively counteracts nocturnal periodic breathing, but it has been investigated almost exclusively in men. Our aim was to explore possible determinants of nocturnal periodic breathing in a high-altitude setting both in men and in women. We hypothesized that increased hypoxic chemosensitivity in men could be associated with the development of nocturnal periodic breathing at altitude more frequently than in women, and that acetazolamide, by leftward shifting the CO2 ventilatory response, could improve nocturnal periodic breathing at altitude in a sex-independent manner.
6837. Ultrasound-guided medical thoracoscopy in the absence of pleural effusion.
作者: Giampietro Marchetti.;Alberto Valsecchi.;Davide Indellicati.;Sabrina Arondi.;Marco Trigiani.;Valentina Pinelli.
来源: Chest. 2015年147卷4期1008-1012页
Medical thoracoscopy (MT) is a diagnostic and therapeutic procedure that permits the study of the pleural space. The presence of pleural adhesions is the most important contraindication to performing MT. Lesions of the pleura in absence of pleural effusion are usually studied in video-assisted thoracoscopic surgery (VATS) with preoperative ultrasound evaluation. No data are available about ultrasound-guided MT in the absence of pleural effusion.
6838. Outcomes after hospitalization in idiopathic pulmonary fibrosis: a cohort study.
作者: A Whitney Brown.;Chelsea P Fischer.;Oksana A Shlobin.;Russell G Buhr.;Shahzad Ahmad.;Nargues A Weir.;Steven D Nathan.
来源: Chest. 2015年147卷1期173-179页
The outcomes of patients with idiopathic pulmonary fibrosis (IPF) who undergo hospitalization have not been well characterized. We sought to determine the frequency of all-cause and respiratory-related hospitalizations and to evaluate their impact on the subsequent course and survival of patients with IPF.
6839. Accuracy of fluorodeoxyglucose-PET imaging for differentiating benign from malignant pleural effusions: a meta-analysis.
作者: José M Porcel.;Paula Hernández.;Montserrat Martínez-Alonso.;Silvia Bielsa.;Antonieta Salud.
来源: Chest. 2015年147卷2期502-512页
The role of fluorodeoxyglucose (FDG)-PET imaging for diagnosing malignant pleural effusions is not well defined. The aim of this study was to summarize the evidence for its use in ruling in or out the malignant origin of a pleural effusion or thickening.
6840. Impact of COPD on the mortality and treatment of patients hospitalized with acute decompensated heart failure: the Worcester Heart Failure Study.
作者: Kimberly A Fisher.;Mihaela S Stefan.;Chad Darling.;Darleen Lessard.;Robert J Goldberg.
来源: Chest. 2015年147卷3期637-645页
COPD is a common comorbidity in patients with heart failure, yet little is known about the impact of this condition in patients with acute decompensated heart failure (ADHF), especially from a more generalizable, community-based perspective. The primary objective of this study was to describe the in-hospital and postdischarge mortality and treatment of patients hospitalized with ADHF according to COPD status.
|