6701. Effect of Using the HEART Score in Patients With Chest Pain in the Emergency Department: A Stepped-Wedge, Cluster Randomized Trial.
作者: Judith M Poldervaart.;Johannes B Reitsma.;Barbra E Backus.;Hendrik Koffijberg.;Rolf F Veldkamp.;Monique E Ten Haaf.;Yolande Appelman.;Herman F J Mannaerts.;Jan-Melle van Dantzig.;Madelon van den Heuvel.;Mohamed El Farissi.;Bernard J W M Rensing.;Nicolette M S K J Ernst.;Ineke M C Dekker.;Frank R den Hartog.;Thomas Oosterhof.;Ghizelda R Lagerweij.;Eugene M Buijs.;Maarten W J van Hessen.;Marcel A J Landman.;Roland R J van Kimmenade.;Luc Cozijnsen.;Jeroen J J Bucx.;Clara E E van Ofwegen-Hanekamp.;Maarten-Jan Cramer.;A Jacob Six.;Pieter A Doevendans.;Arno W Hoes.
来源: Ann Intern Med. 2017年166卷10期689-697页
The HEART (History, Electrocardiogram, Age, Risk factors, and initial Troponin) score is an easy-to-apply instrument to stratify patients with chest pain according to their short-term risk for major adverse cardiac events (MACEs), but its effect on daily practice is unknown.
6702. Hepatitis B Virus Reactivation Associated With Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus: A Review of Cases Reported to the U.S. Food and Drug Administration Adverse Event Reporting System.
作者: Susan J Bersoff-Matcha.;Kelly Cao.;Mihaela Jason.;Adebola Ajao.;S Christopher Jones.;Tamra Meyer.;Allen Brinker.
来源: Ann Intern Med. 2017年166卷11期792-798页
Direct-acting antiviral agents (DAAs) are used increasingly to treat hepatitis C virus (HCV) infection. Reports were published recently on hepatitis B virus (HBV) reactivation (HBV-R) in patients with HBV-HCV co-infection. Hepatitis B virus reactivation, defined as an abrupt increase in HBV replication in patients with inactive or resolved HBV infection, may result in clinically significant hepatitis.
6703. Mindfulness-Based Stress Reduction for Treating Low Back Pain: A Systematic Review and Meta-analysis.
作者: Dennis Anheyer.;Heidemarie Haller.;Jürgen Barth.;Romy Lauche.;Gustav Dobos.;Holger Cramer.
来源: Ann Intern Med. 2017年166卷11期799-807页
Mindfulness-based stress reduction (MBSR) is frequently used to treat pain-related conditions, but its effects on low back pain are uncertain.
6707. Lectures on Inhumanity: Teaching Medical Ethics in German Medical Schools Under Nazism.
Nazi medicine and its atrocities have been explored in depth over the past few decades, but scholars have started to examine medical ethics under Nazism only in recent years. Given the medical crimes and immoral conduct of physicians during the Third Reich, it is often assumed that Nazi medical authorities spurned ethics. However, in 1939, Germany introduced mandatory lectures on ethics as part of the medical curriculum. Course catalogs and archival sources show that lectures on ethics were an integral part of the medical curriculum in Germany between 1939 and 1945. Nazi officials established lecturer positions for the new subject area, named Medical Law and Professional Studies, at every medical school. The appointed lecturers were mostly early members of the Nazi Party and imparted Nazi political and moral values in their teaching. These values included the unequal worth of human beings, the moral imperative of preserving a pure Aryan people, the authoritarian role of the physician, the individual's obligation to stay healthy, and the priority of public health over individual-patient care. This article shows that there existed not only a Nazi version of medical ethics but also a systematic teaching of such ethics to students in Nazi Germany. The findings illustrate that, from a historical point of view, the notion of "eternal values" that are inherent to the medical profession is questionable. Rather, the prevailing medical ethos can be strongly determined by politics and the zeitgeist and therefore has to be repeatedly negotiated.
6715. Cost-Effectiveness of Sacubitril-Valsartan in Patients Who Have Heart Failure With Reduced Ejection Fraction.
作者: Alexander T Sandhu.;Daniel A Ollendorf.;Richard H Chapman.;Steven D Pearson.;Paul A Heidenreich.
来源: Ann Intern Med. 2017年166卷8期607-608页 |