6591. CONSORT Statement for Randomized Trials of Nonpharmacologic Treatments: A 2017 Update and a CONSORT Extension for Nonpharmacologic Trial Abstracts.
作者: Isabelle Boutron.;Douglas G Altman.;David Moher.;Kenneth F Schulz.;Philippe Ravaud.; .
来源: Ann Intern Med. 2017年167卷1期40-47页
Incomplete and inadequate reporting is an avoidable waste that reduces the usefulness of research. The CONSORT (Consolidated Standards of Reporting Trials) Statement is an evidence-based reporting guideline that aims to improve research transparency and reduce waste. In 2008, the CONSORT Group developed an extension to the original statement that addressed methodological issues specific to trials of nonpharmacologic treatments (NPTs), such as surgery, rehabilitation, or psychotherapy. This article describes an update of that extension and presents an extension for reporting abstracts of NPT trials. To develop these materials, the authors reviewed pertinent literature published up to July 2016; surveyed authors of NPT trials; and conducted a consensus meeting with editors, trialists, and methodologists. Changes to the CONSORT Statement extension for NPT trials include wording modifications to improve readers' understanding and the addition of 3 new items. These items address whether and how adherence of participants to interventions is assessed or enhanced, description of attempts to limit bias if blinding is not possible, and specification of the delay between randomization and initiation of the intervention. The CONSORT extension for abstracts of NPT trials includes 2 new items that were not specified in the original CONSORT Statement for abstracts. The first addresses reporting of eligibility criteria for centers where the intervention is performed and for care providers. The second addresses reporting of important changes to the intervention versus what was planned. Both the updated CONSORT extension for NPT trials and the CONSORT extension for NPT trial abstracts should help authors, editors, and peer reviewers improve the transparency of NPT trial reports.
6594. Use of the Dual-Antiplatelet Therapy Score to Guide Treatment Duration After Percutaneous Coronary Intervention.
作者: Raffaele Piccolo.;Giuseppe Gargiulo.;Anna Franzone.;Andrea Santucci.;Sara Ariotti.;Andrea Baldo.;Carlo Tumscitz.;Aris Moschovitis.;Stephan Windecker.;Marco Valgimigli.
来源: Ann Intern Med. 2017年167卷1期17-25页
The dual-antiplatelet therapy (DAPT) score was developed to identify patients more likely to derive harm (score <2) or benefit (score ≥2) from prolonged DAPT after percutaneous coronary intervention (PCI).
6596. Racial Differences in the Relationship of Glucose Concentrations and Hemoglobin A1c Levels.
作者: Richard M Bergenstal.;Robin L Gal.;Crystal G Connor.;Rose Gubitosi-Klug.;Davida Kruger.;Beth A Olson.;Steven M Willi.;Grazia Aleppo.;Ruth S Weinstock.;Jamie Wood.;Michael Rickels.;Linda A DiMeglio.;Kathleen E Bethin.;Santica Marcovina.;Andreana Tassopoulos.;Sooji Lee.;Elaine Massaro.;Suzan Bzdick.;Brian Ichihara.;Eileen Markmann.;Paul McGuigan.;Stephanie Woerner.;Michelle Ecker.;Roy W Beck.; .
来源: Ann Intern Med. 2017年167卷2期95-102页
Debate exists as to whether the higher hemoglobin A1c (HbA1c) levels observed in black persons than in white persons are due to worse glycemic control or racial differences in the glycation of hemoglobin.
6599. Presence of Human Hepegivirus-1 in a Cohort of People Who Inject Drugs.
作者: Abraham J Kandathil.;Florian P Breitwieser.;Jaiprasath Sachithanandham.;Matthew Robinson.;Shruti H Mehta.;Winston Timp.;Steven L Salzberg.;David L Thomas.;Ashwin Balagopal.
来源: Ann Intern Med. 2017年167卷1期1-7页
Next-generation metagenomic sequencing (NGMS) has opened new frontiers in microbial discovery but has been clinically characterized in only a few settings.
|