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6265. Outcomes of Dabigatran and Warfarin for Atrial Fibrillation in Contemporary Practice: A Retrospective Cohort Study.
作者: Alan S Go.;Daniel E Singer.;Sengwee Toh.;T Craig Cheetham.;Marsha E Reichman.;David J Graham.;Mary Ross Southworth.;Rongmei Zhang.;Rima Izem.;Margie R Goulding.;Monika Houstoun.;Katrina Mott.;Sue Hee Sung.;Joshua J Gagne.
来源: Ann Intern Med. 2017年167卷12期845-854页
Dabigatran (150 mg twice daily) has been associated with lower rates of stroke than warfarin in trials of atrial fibrillation, but large-scale evaluations in clinical practice are limited.
6266. Diagnostic Accuracy of Screening Tests and Treatment for Post-Acute Coronary Syndrome Depression: A Systematic Review.
作者: Jason A Nieuwsma.;John W Williams.;Natasha Namdari.;Jeffrey B Washam.;Giselle Raitz.;James A Blumenthal.;Wei Jiang.;Roshini Yapa.;Amanda J McBroom.;Kathryn Lallinger.;Robyn Schmidt.;Andrzej S Kosinski.;Gillian D Sanders.
来源: Ann Intern Med. 2017年167卷10期725-735页
Patients who have had an acute coronary syndrome (ACS) event have an increased risk for depression.
6268. Functional Impairment and Decline in Middle Age: A Cohort Study.
作者: Rebecca T Brown.;L Grisell Diaz-Ramirez.;W John Boscardin.;Sei J Lee.;Michael A Steinman.
来源: Ann Intern Med. 2017年167卷11期761-768页
Difficulties with daily functioning are common in middle-aged adults. However, little is known about the epidemiology or clinical course of these problems, including the extent to which they share common features with functional impairment in older adults.
6269. Self-administered Versus Directly Observed Once-Weekly Isoniazid and Rifapentine Treatment of Latent Tuberculosis Infection: A Randomized Trial.
作者: Robert Belknap.;David Holland.;Pei-Jean Feng.;Joan-Pau Millet.;Joan A Caylà.;Neil A Martinson.;Alicia Wright.;Michael P Chen.;Ruth N Moro.;Nigel A Scott.;Bert Arevalo.;José M Miró.;Margarita E Villarino.;Marc Weiner.;Andrey S Borisov.; .
来源: Ann Intern Med. 2017年167卷10期689-697页
Expanding latent tuberculosis treatment is important to decrease active disease globally. Once-weekly isoniazid and rifapentine for 12 doses is effective but limited by requiring direct observation.
6270. Epizootic Outbreak of Yellow Fever Virus and Risk for Human Disease in Salvador, Brazil.
作者: Igor Adolfo Dexheimer Paploski.;Raquel Lima Souza.;Laura Beatriz Tauro.;Cristiane Wanderley Cardoso.;Vánio André Mugabe.;Anna Beatriz Pereira Simões Alves.;Joice de Jesus Gomes.;Mariana Kikuti.;Gubio Soares Campos.;Sílvia Sardi.;Scott C Weaver.;Mitermayer Galvão Reis.;Uriel Kitron.;Guilherme Sousa Ribeiro.
来源: Ann Intern Med. 2018年168卷4期301-302页 6278. Acute Kidney Injury.
Acute kidney injury is a heterogeneous group of conditions characterized by a sudden decrease in glomerular filtration rate, manifested by an increase in serum creatinine concentration or oliguria, and classified by stage and cause. This type of injury occurs in approximately 20% of hospitalized patients, with major complications including volume overload, electrolyte disorders, uremic complications, and drug toxicity. Management includes specific treatments according to the underlying cause and supportive treatment to prevent and manage complications. Kidney replacement therapy is used when complications cannot be managed with medical therapy alone. Despite advances in care, the mortality rate in patients requiring kidney replacement therapy remains approximately 50%.
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