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42. Efficacy and Safety of SGLT2 Inhibitors in Heart Failure: Observational Evidence in Geriatric Patients AGING-HF.
作者: Abdelhakim Hacil.;Yara Antakly Hanon.;Audrey Lacour.;Jean-Philippe David.;Tesnim Khalifa.;Matthieu Piccoli.;Aude Clemencin.;Patrick Assayag.;Jean-Sebastien Vidal.;Olivier Hanon.
来源: Circ Heart Fail. 2025年e012794页
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have shown beneficial effects in heart failure (HF) management, but data on their use in geriatric populations with high comorbidity remain limited. This observational study aimed to assess the real-world efficacy and safety of SGLT2i in elderly patients with HF.
43. Sarcopenia Assessment Using Fully Automated Deep Learning Predicts Cardiac Allograft Survival in Heart Transplant Recipients.
作者: Frederick M Lang.;Jianfei Liu.;Kevin J Clerkin.;Elissa A Driggin.;Andrew J Einstein.;Gabriel T Sayer.;Koji Takeda.;Nir Uriel.;Ronald M Summers.;Veli K Topkara.
来源: Circ Heart Fail. 2025年e012805页
Sarcopenia is associated with adverse outcomes in patients with end-stage heart failure. Muscle mass can be quantified via manual segmentation of computed tomography images, but this approach is time-consuming and subject to interobserver variability. We sought to determine whether fully automated assessment of radiographic sarcopenia by deep learning would predict heart transplantation outcomes.
44. Natriuretic Peptide Cut Points for Heart Failure Classification in Individuals With and Without Obesity.
作者: Mandana Chitsazan.;Juhi K Parekh.;Leah B Kosyakovsky.;Sophie M Nemeth.;Emily S Lau.;James L Januzzi.;Thomas J Wang.;Daniel Levy.;Chiadi E Ndumele.;Elizabeth Selvin.;Christie Ballantyne.;Bruce M Psaty.;John S Gottdiener.;Jorge R Kizer.;Christopher R deFilippi.;Norrina B Allen.;Rudolf A de Boer.;Sanjiv J Shah.;Jennifer E Ho.
来源: Circ Heart Fail. 2025年e013112页
The 2022 American Heart Association/American College of Cardiology/Heart Failure Society of America guidelines introduced elevated natriuretic peptide (NP) levels as a criterion for defining stage B heart failure (HF), or pre-HF, to identify individuals at greatest risk for future HF. Given the known NP deficiency in obesity, we aimed to assess whether a single NP cut point would disproportionately up-classify individuals with versus without obesity to stage B HF.
45. Changes in Heart Transplant Listings by Insurance and Race During the COVID Public Health Emergency.
作者: Daniel K Fox.;R J Waken.;Fengxian Wang.;Khavya Avula.;David S Raymer.;Justin Vader.;Joel Schilling.;Karen E Joynt Maddox.
来源: Circ Heart Fail. 2025年e012306页
Socioeconomic inequities in access to heart transplantation, including those based on insurance coverage and race or ethnicity, are well documented. During the COVID pandemic, the federal government declared a Public Health Emergency (PHE), which prevented states from disenrolling people from Medicaid. We sought to determine whether this policy was associated with changes in the insurance or racial composition of the heart transplant waiting list.
46. National Patterns of Remote Patient Monitoring Service Availability at US Hospitals.
作者: Aline F Pedroso.;Zhenqiu Lin.;Joseph S Ross.;Rohan Khera.
来源: Circ Cardiovasc Qual Outcomes. 2025年e012034页
Digital remote patient monitoring (RPM), such as home-based blood pressure, heart rate, or weight monitoring, enables longitudinal care outside traditional health care settings, especially in the vulnerable period after hospitalizations, with broad coverage of the service by payers. We sought to evaluate patterns of RPM service availability at US hospitals and the characteristics of hospitals and the counties they serve that are associated with the availability of these services.
47. Transjugular Approach for Evoque Transcatheter Tricuspid Valve Replacement in Patients With Challenging Anatomy.
作者: Jonathan X Fang.;Pedro A Villablanca.;Tiberio M Frisoli.;Gennaro Giustino.;Leo Kar Lok Lai.;James C Lee.;Pedro Engel Gonzalez.;Bryan Zweig.;Hussayn Alrayes.;Georgi K Fram.;Felix Nguyen.;Ahmad Jabri.;Tyler Andrews.;Omar Abdelhai.;Gautam Rangavajla.;William W O'Neill.;Brian P O'Neill.
来源: Circ Cardiovasc Interv. 2025年e015276页
The Evoque system is the first commercially available transcatheter tricuspid valve replacement (TTVR) system in the United States. However, challenging anatomy in real-world patients could preclude successful transfemoral Evoque TTVR. We aim to investigate the feasibility of the transjugular Evoque TTVR in anatomy unsuitable for a transfemoral approach.
48. Safety and Effectiveness of Intracoronary Imaging-Guided PCI in Contemporary Practice: Insights From BMC2.
作者: Thomas Basala.;Milan Seth.;Ryan D Madder.;Brett Wanamaker.;Brittany Fuller.;Evan Shlofmitz.;Edouard Daher.;Michael Tucciarone.;Chadi Alraies.;Amir Kaki.;Sunil V Rao.;Hitinder S Gurm.;Devraj Sukul.
来源: Circ Cardiovasc Interv. 2025年e014886页
Studies suggest percutaneous coronary intervention (PCI) guided by intracoronary imaging (ICI) results in larger balloon/stent diameters and longer stents. Whether this occurs in real-world PCI is poorly understood.
49. Response by Demir et al to Letter Regarding Article, "Pressure Derived Indices in the Left Main Coronary Artery: Insights From Comprehensive In Vivo Hemodynamic Studies of Diseased and Unobstructed Vessels".50. American Heart Association National Integrated ASCVD Initiative: An Implementation Initiative to Improve Lipid Management Among Patients With ASCVD.
作者: Chiadi E Ndumele.;Ankeet S Bhatt.;Lynne T Braun.;Steven Chen.;Seth S Martin.;Michael T Mullen.;Nishant P Shah.;Stephen L Sigal.;Tracy Yu-Ping Wang.;Rebecca Alicki.;Chandler Beon.;Haoyun Hong.;Sara O'Kane.;Katherine J Overton.;Kathie Thomas.;Howard Haft.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷8期e011627页 51. Cost-Effectiveness of Hypertension Treatment According to 2017 American College of Cardiology and American Heart Association Guidelines.
作者: Joanne M Penko.;Brandon K Bellows.;Susan Hennessy.;Dhruv S Kazi.;Ross Boylan.;Yiyi Zhang.;Pamela G Coxson.;Lee Goldman.;Kirsten Bibbins-Domingo.;Andrew E Moran.
来源: Circ Cardiovasc Qual Outcomes. 2025年18卷8期e011872页
Compared with the 2003 Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) guideline, the 2017 American College of Cardiology and American Heart Association guideline (ACC/AHA 2017) expanded hypertension diagnostic criteria to blood pressure (BP) ≥130/80 mm Hg and intensified treatment goals to <130/80 mm Hg. The cost-effectiveness of ACC/AHA 2017 guideline treatment has not been quantified.
54. Letter by Kornelius Regarding Article, "Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial".55. Reformulation of the Necroptosis Pathway in Reperfused Myocardial Infarction.
作者: Dongze Qin.;Radheshyam Modanwal.;Madeeha Ghazi.;J Jose Corbalan.;Xiaotong F Jia.;Joshua L Axelrod.;Roneldine Mesidor.;Hee Jae Jang.;Claudio Humeres.;Anis Hanna.;Fahimeh Varzideh.;Michelle D Tallquist.;Gaetano Santulli.;Qinghang Liu.;Lorrie A Kirshenbaum.;Hongmin Ni.;Timothy J Kamp.;Rebekah L Gundry.;Siddharth Balachandran.;Alexei Degterev.;John W Calvert.;Richard N Kitsis.
来源: Circulation. 2025年152卷7期486-488页 56. Response by Docherty et al to Letter Regarding Article, "Efficacy and Safety of Finerenone Across the Ejection Fraction Spectrum in Heart Failure With Mildly Reduced or Preserved Ejection Fraction: A Prespecified Analysis of the FINEARTS-HF Trial".
作者: Kieran F Docherty.;Alasdair D Henderson.;Pardeep S Jhund.;Scott D Solomon.;John J V McMurray.
来源: Circulation. 2025年152卷7期e65-e66页 58. An Aberrant Resurgence of Endogenous Retroviruses Prompts Myocarditis and Heart Failure.
作者: Junhao Xiong.;Shasha Zhang.;Zilong Geng.;Juntao Lin.;Kang Cheng.;Huan Hu.;Yuze Wang.;Xing Liu.;Yuanzhe Sheng.;Ping Yang.;Yige Li.;Shuo Wu.;Xiao Cheng.;Yelan Li.;Aijun Sun.;Alex F Chen.;Daowen Wang.;Chen Chen.;Yan Zhang.;Gengze Wu.;Chunyu Zeng.;Xiaoling Guo.;Xumin Hou.;Ruogu Li.;Yuliang Feng.;Dan Zhu.;Kun Sun.;Bing Zhang.
来源: Circulation. 2025年
Endogenous retroviruses (ERVs) occupy >8% of the human genome. Aberrant resurgence of ERVs has been implicated recently in several critical pathologies. However, the possible incidence and role of ERV resurgence in heart failure (HF), a leading cause of global morbidity and mortality, remain unexplored.
60. Transcatheter Aortic Valve Replacement With Balloon- Versus Self-Expandable Bioprostheses for the Treatment of Bicuspid Aortic Valve Stenosis.
作者: Daniele Giacoppo.;Hector Alvarez-Covarrubias.;Erion Xhepa.;Yuji Matsuda.;Stefano Cangemi.;Jonathan M Michel.;Anna Sannino.;Johannes Ziegelmüller.;Enrico Criscione.;Motoki Fukutomi.;Manuel Hein.;Romain Didier.;David Meier.;Taishi Okuno.;Sebastian Ludwig.;Marco Ancona.;Dimitry Schewel.;Tommaso Fabris.;Flavien Vincent.;Lisa Voigtlaender.;Francesca Ziviello.;Richard Tanner.;Claudia Tamburino.;Hendrik Ruge.;Mattia Lunardi.;Pablo Codner.;Marco Barbanti.;Fabian Nietlispach.;Holger Nef.;Ivan Casserly.;Vasilis Babaliaros.;Tchetche Didier.;Rudiger Lange.;Martine Gilard.;Matteo Montorfano.;Martin Landt.;Paul Grayburn.;Philipp Ruile.;Nicolas M Van Mieghem.;Francesco Bedogni.;George Dangas.;Corrado Tamburino.;Niklas Schofer.;Francesco Burzotta.;Eric Van Belle.;Franz-Josef Neumann.;Ran Kornowski.;Flavio Ribichini.;Darren Mylotte.;Stephan Windecker.;Gert Richardt.;Lars Sondergaard.;John G Webb.;Giuseppe Tarantini.;Thomas Pilgrim.;Roxana Mehran.;Davide Capodanno.;Adnan Kastrati.;Michael Joner.;Mark S Spence.;Albert M Kasel.;Robert A Byrne.
来源: Circulation. 2025年
Differences between balloon- and self-expandable transcatheter heart valves (BE-THVs and SE-THVs, respectively) may influence the outcomes of transcatheter aortic valve replacement for bicuspid aortic valve (BAV) stenosis.
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