41. Association between a Recalled Positive Airway Pressure (PAP) Device and Obstructive Lung Disease: A Province-Based Study.
作者: Tetyana Kendzerska.;Robert Talarico.;Marcus Povitz.;Kenneth Blades.;Constance Mackenzie.;Andrea S Gershon.;Najib T Ayas.;Marta Kaminska.;Mark Fenton.;Kerry A McBrien.;Steven Hawken.;Diana Ratycz.;Robert L Owens.;Sachin R Pendharkar.
来源: Chest. 2025年
Limited real-world data exist on the health impacts of the Philips Respironics recall for positive airway pressure (PAP) devices.
42. How I do it: Best practices for right heart catheterization in the diagnosis of pulmonary hypertension.
作者: Yuri Matusov.;Nicholas A Kolaitis.;Dael Geft.;Jacqueline DesJardin.;Christopher Barnett.;Antoine Hage.;Teresa De Marco.;Michael I Lewis.
来源: Chest. 2025年
Right heart catheterization (RHC) is the gold standard for the diagnosis of pulmonary hypertension (PH). There are variations in practice and several pitfalls introducing errors in diagnosis that can significantly impact treatment. Errors in assessing the correct pulmonary artery wedge pressure (PAWP) can significantly affect accurate classification of patients with pulmonary hypertension, and lead to potentially deleterious treatment decisions. This review focuses on best practices in RHC performance, emphasizing practical and pathophysiologic principles to obtain the most accurate result, as well as advanced applications in PH.
43. Health and Utilization Burden of Obstructive Sleep Apnea among U.S. Active-Duty Military Personnel.
作者: Emerson M Wickwire.;Vincent F Capaldi.;Jeph Herrin.;Benoit Stryckman.;Connie Thomas.;Scott G Williams.;J Kent Werner.;Wendy Funk.;Thomas Nassif.;Jennifer S Albrecht.
来源: Chest. 2025年
Despite the significant health and economic burden associated with obstructive sleep apnea (OSA) among civilians, little is known about this burden among active-duty military personnel.
44. Proteomic Analysis of Nasopharyngeal Aspirate Biomarkers for Prematurity-Related Bronchopulmonary Dysplasia.
作者: Fernando Garrido-Muñoz.;Alejandro Fernández-Vega.;Rebeca Gregorio-Hernández.;Marta Padín-Fontán.;Mónica de Las Heras-Martín.;Marta Teresa-Palacio.;Paula Alonso-Quintela.;Alberto Trujillo-Fagundo.;Alba Pérez-Pérez.;Marcelino Pumarada-Prieto.;Jon Montero-Gato.;Victoria Aldecoa-Bilbao.;Ignacio Oulego-Erroz.;Mario Sánchez-Fernández.;Almudena Alonso-Ojembarrena.
来源: Chest. 2025年
The high incidence of bronchopulmonary dysplasia (BPD) continues to be a problem among extremely low-gestational-age neonates (ELGANs). Recent improvements in next-generation proteomics have provided opportunities to obtain new perspectives on the early detection of BPD. In this study, our main objectives were to study the proteomes of patients by collecting nasopharyngeal aspirate (NPA) samples and evaluate the differences between ELGANs with and without BPD at 1 week of life.
45. Lung Function Decline and Airflow Limitation Risk in Preserved Ratio Impaired Spirometry Subtypes by Smoking Status.
作者: Cuiqiong Dai.;Fan Wu.;Jia Tian.;Jiangyu Cui.;Zhishan Deng.;Heshen Tian.;Peiyu Huang.;Huajing Yang.;Youlan Zheng.;Zihui Wang.;Shan Xiao.;Xiang Wen.;Lifei Lu.;Ningning Zhao.;Changli Yang.;Shuqing Yu.;Shengming Liu.;Dali Wang.;Xiaoping Wang.;Jiachun Lu.;Nanshan Zhong.;Yumin Zhou.;Pixin Ran.
来源: Chest. 2025年
Preserved ratio impaired spirometry (PRISm) is regarded as a COPD precursor, but whether this varies by smoking status remains unclear.
47. The Impact of Health Care Disparities on Lung Cancer Screening and Treatment.
作者: Brett Bade.;Saadia A Faiz.;Miranda Tan.;Aaron D Baugh.;Mark Lavercombe.;Ajay Sheshadri.
来源: Chest. 2025年
From screening to treatment, the continuum of lung cancer reflects unequal access and delivery, with more vulnerable patients less able to receive high-quality care. Despite great advances in lung cancer care (eg, screening and nodule programs to identify early-stage disease and immune-mediated and targeted therapies for advanced-stage disease), disparities persist both in the United States and globally. In this narrative review, the spectrum of disparities that influence lung cancer care on a national scale, including race, ethnicity, age, socioeconomic status, geographic location, and insurance access, are explored. The review focuses on how disparities impact screening efforts and lung cancer treatments. Where data are available, trends on a global scale are addressed. Potential solutions are offered to address recognized disparities, primarily by identifying pertinent social determinants of health and launching multipronged interventions to improve the care of all patients with lung cancer.
48. Pregnancy Outcomes in 53 Female Lung Transplant Recipients.
Limited data exists to inform and appropriately counsel female lung transplant (LuT) recipients regarding post-transplant pregnancy.
57. A 7-Year-Old Girl With Multiple Pulmonary Nodules.
作者: Jie Jiang.;Yamin Rao.;Chenglei Liu.;Shih-Jen Chang.;Yajing Qiu.;Xiaoxi Lin.
来源: Chest. 2025年167卷5期e161-e165页
A 7-year-old girl was referred to our vascular anomaly center for further evaluation of multiple lung nodules. These nodules were incidentally detected on a CT scan during hospitalization for treatment of mycoplasma pneumonia at another hospital. The biopsy results suggested the possibility of vascular tumors. Physical examination revealed clear breath sounds without rales. Furthermore, no skin lesions or other positive signs were observed. The patient was not receiving supplemental oxygen. Before she came to our center, the patient had received antibiotic treatment for mycoplasma pneumonia. The CT scan after recovery revealed that the multiple nodules in both lungs persisted despite the resolution of the infection.
59. Lipoid Pneumonia Following Chronic Aspiration of Cannabis Oil Used for the Treatment of Seizures.
作者: Nacera Hanzal.;Gunjan Sanjay Mhapankar.;Erick Sell.;Joseph de Nanassy.;Dhenuka Radhakrishnan.
来源: Chest. 2025年167卷5期e149-e154页
A 4-year-old girl with ring chromosome 14, epilepsy, global developmental delay, and failure to thrive presented for a preoperative assessment for gastrostomy tube (G-tube) insertion and was incidentally found to be hypoxemic, with saturations of 81% in room air. There was no history of fever or upper respiratory tract infection symptoms; however, her parents described a progressive history of choking and emesis with feeds over 3 months. Chest radiograph demonstrated patchy alveolar opacities in the right lower and middle lobes. She was admitted to the hospital and treated with supplemental oxygen and IV ampicillin for a suspected aspiration pneumonia. On day 3 of her admission, because of persistent hypoxemia despite high-flow nasal cannula support at 2 L/kg/min with an Fio2 of 0.6 to 0.7, and frequent need for suctioning of thick yellow secretions, she was transferred to the PICU for escalation to noninvasive ventilation. Because of poor response after 7 days, and respiratory secretions showing moderate growth of Klebsiella oxytoca and light growth of Stenotrophomonas maltophilia, sulfamethoxazole-trimethoprim was added. Azithromycin was also started on day 8 to cover atypical pathogens, then discontinued when Mycoplasma pneumoniae polymerase chain reaction was negative.
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