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5421. Swan, Ganz, and Their Catheter: Its Evolution Over the Past Half Century.
Jeremy Swan and William Ganz developed their eponymous pulmonary artery (PA) catheter in the 1970s and, in the process, revolutionized measurement of cardiac output, pressures within the left side of the heart, and resistance in systemic and pulmonary circulations. Their invention enabled diagnostic measurements at the bedside and contributed to the birth of critical care medicine; technologic advances preceding the PA catheter generally could not be used at the bedside and required patients to be stable enough to be taken to the catheterization laboratory. Swan and Ganz worked in the same department but had quite dissimilar backgrounds and personalities. This article describes their lives and careers, the state of intensive care before and after their catheter was introduced, and the natural life cycle the PA catheter faced as new, less invasive technology arrived to replace it.
5434. Use of High-Sensitivity Cardiac Troponin for the Exclusion of Inducible Myocardial Ischemia: A Cohort Study.
作者: Muhammad Hammadah.;Jeong Hwan Kim.;Ayman Samman Tahhan.;Bryan Kindya.;Chang Liu.;Yi-An Ko.;Ibhar Al Mheid.;Kobina Wilmot.;Ronnie Ramadan.;Ayman Alkhoder.;Fahad Choudhary.;Mohamad Mazen Gafeer.;Naser Abdelhadi.;Pratik Pimple.;Pratik Sandesara.;Bruno B Lima.;Amit J Shah.;Laura Ward.;Michael Kutner.;J Douglas Bremner.;David S Sheps.;Paolo Raggi.;Laurence S Sperling.;Viola Vaccarino.;Arshed A Quyyumi.
来源: Ann Intern Med. 2018年169卷11期751-760页
Many patients with coronary artery disease (CAD) are routinely referred for surveillance stress testing despite recommendations against it.
5435. Comparative Effectiveness and Safety of Bariatric Procedures for Weight Loss: A PCORnet Cohort Study.
作者: David Arterburn.;Robert Wellman.;Ana Emiliano.;Steven R Smith.;Andrew O Odegaard.;Sameer Murali.;Neely Williams.;Karen J Coleman.;Anita Courcoulas.;R Yates Coley.;Jane Anau.;Roy Pardee.;Sengwee Toh.;Cheri Janning.;Andrea Cook.;Jessica Sturtevant.;Casie Horgan.;Kathleen M McTigue.; .
来源: Ann Intern Med. 2018年169卷11期741-750页
There has been a dramatic shift in use of bariatric procedures, but little is known about their long-term comparative effectiveness.
5436. On-Demand Sildenafil as a Treatment for Raynaud Phenomenon: A Series of n-of-1 Trials.
作者: Matthieu Roustit.;Joris Giai.;Olivier Gaget.;Charles Khouri.;Myriam Mouhib.;Adrien Lotito.;Sophie Blaise.;Christophe Seinturier.;Fabien Subtil.;Adeline Paris.;Claire Cracowski.;Bernard Imbert.;Patrick Carpentier.;Sunita Vohra.;Jean-Luc Cracowski.
来源: Ann Intern Med. 2018年169卷10期694-703页
Treatment of Raynaud phenomenon (RP) with phosphodiesterase-5 inhibitors has shown moderate efficacy. Adverse effects decrease the risk-benefit profile of these drugs, and patients may not be willing to receive long-term treatment. On-demand single doses before or during exposure to cold may be a good alternative.
5437. Interventions for Preventing Thromboembolic Events in Patients With Atrial Fibrillation: A Systematic Review.
作者: Angela Lowenstern.;Sana M Al-Khatib.;Lauren Sharan.;Ranee Chatterjee.;Nancy M Allen LaPointe.;Bimal Shah.;Ethan D Borre.;Giselle Raitz.;Adam Goode.;Roshini Yapa.;J Kelly Davis.;Kathryn Lallinger.;Robyn Schmidt.;Andrzej S Kosinski.;Gillian D Sanders.
来源: Ann Intern Med. 2018年169卷11期774-787页
The comparative safety and effectiveness of treatments to prevent thromboembolic complications in atrial fibrillation (AF) remain uncertain.
5438. Reducing Firearm Injuries and Deaths in the United States: A Position Paper From the American College of Physicians.
作者: Renee Butkus.;Robert Doherty.;Sue S Bornstein.; .;Jan K Carney.;Tom Cooney.;Lee Engel.;Heather E Gantzer.;Tracey L Henry.;Joshua D Lenchus.;Bridget M McCandless.;Jacob Quinton.;Molly Southworth.;Alexandria Valdrighi.;Mary Anderson Wallace.
来源: Ann Intern Med. 2018年169卷10期704-707页
For more than 20 years, the American College of Physicians (ACP) has advocated for the need to address firearm-related injuries and deaths in the United States. Yet, firearm violence continues to be a public health crisis that requires the nation's immediate attention. The policy recommendations in this paper build on, strengthen, and expand current ACP policies approved by the Board of Regents in April 2014, based on analysis of approaches that the evidence suggests will be effective in reducing deaths and injuries from firearm-related violence.
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