4957. Cases in Precision Medicine: The Role of Pharmacogenetics in Precision Prescribing.
Pharmacogenetics may help physicians deliver individualized treatments based on how a person's genes affect a drug's effects and metabolism. This information can help prevent adverse events or improve drug efficacy by enabling the physician to optimize dosage or to avoid a medication with adverse reactions and to prescribe an alternative therapy. This article discusses the current clinical utility of pharmacogenetic testing in the context of a patient who requires anticoagulation with warfarin.
4958. Risk of Biologics and Glucocorticoids in Patients With Rheumatoid Arthritis Undergoing Arthroplasty: A Cohort Study.
作者: Michael D George.;Joshua F Baker.;Kevin Winthrop.;Evo Alemao.;Lang Chen.;Sean Connolly.;Jesse Y Hsu.;Teresa A Simon.;Qufei Wu.;Fenglong Xie.;Shuo Yang.;Jeffrey R Curtis.
来源: Ann Intern Med. 2019年170卷12期825-836页
Patients with rheumatoid arthritis (RA) are at increased risk for infection after arthroplasty, yet risks of specific biologic medications are unknown.
4959. Variation Among Primary Care Physicians in 30-Day Readmissions.
作者: Siddhartha Singh.;James S Goodwin.;Jie Zhou.;Yong-Fang Kuo.;Ann B Nattinger.
来源: Ann Intern Med. 2019年170卷11期749-755页
Whether readmission rates vary by primary care physician (PCP) is unknown, although federal policy holds PCPs accountable for reducing readmissions.
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