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4201. Comparative Pricing of Branded Tenofovir Alafenamide-Emtricitabine Relative to Generic Tenofovir Disoproxil Fumarate-Emtricitabine for HIV Preexposure Prophylaxis: A Cost-Effectiveness Analysis.
作者: Rochelle P Walensky.;Tim Horn.;Nicole C McCann.;Kenneth A Freedberg.;A David Paltiel.
来源: Ann Intern Med. 2020年172卷9期583-590页
Tenofovir alafenamide-emtricitabine (F/TAF) was recently approved as a noninferior and potentially safer option than tenofovir disoproxil fumarate-emtricitabine (F/TDF) for HIV preexposure prophylaxis (PrEP) in the United States.
4207. Fibromyalgia.
Fibromyalgia is characterized by chronic, widespread musculoskeletal pain and associated fatigue, sleep disturbances, and other cognitive and somatic symptoms. For many patients, these symptoms persist for years and lead to frequent health care use; for some, fibromyalgia and its symptoms can be debilitating. Although many treatments are available, management remains challenging. This article highlights the clinical features of fibromyalgia, discusses diagnostic criteria and their evolution, and reviews treatment options.
4216. Managing Emerging Infectious Diseases: Should Travel Be the Fifth Vital Sign?
In the setting of emerging infections, such as COVID-19, this commentary argues that all members of the health care team need training on how to integrate key epidemiologic information, such as travel history, into their risk assessments in the same way they are trained to ask about tobacco exposure to assess cancer and heart disease risk.
4217. Pharmacotherapy for the Treatment of Cannabis Use Disorder: A Systematic Review.
作者: Karli K Kondo.;Benjamin J Morasco.;Shannon M Nugent.;Chelsea K Ayers.;Maya E O'Neil.;Michele Freeman.;Devan Kansagara.
来源: Ann Intern Med. 2020年172卷6期398-412页
Cannabis use disorder (CUD) is a growing concern, and evidence-based data are needed to inform treatment options.
4218. The Effect of Influenza Vaccination for the Elderly on Hospitalization and Mortality: An Observational Study With a Regression Discontinuity Design.
Observational studies using traditional research designs suggest that influenza vaccination reduces hospitalizations and mortality among elderly persons. Accordingly, health authorities in some countries prioritize vaccination of this population. Nevertheless, questions remain about this policy's effectiveness given the potential for bias and confounding in observational data.
4219. Continuation of Annual Screening Mammography and Breast Cancer Mortality in Women Older Than 70 Years.
作者: Xabier García-Albéniz.;Miguel A Hernán.;Roger W Logan.;Mary Price.;Katrina Armstrong.;John Hsu.
来源: Ann Intern Med. 2020年172卷6期381-389页
Randomized trials have shown that initiating breast cancer screening between ages 50 and 69 years and continuing it for 10 years decreases breast cancer mortality. However, no trials have studied whether or when women can safely stop screening mammography. An estimated 52% of women aged 75 years or older undergo screening mammography in the United States.
4220. The Impact of a Sweetened Beverage Tax on Beverage Volume Sold in Cook County, Illinois, and Its Border Area.
Sugar-sweetened beverage (SSB) consumption is linked to adverse health outcomes.
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