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4101. A 48-Year-Old South African Woman with Rheumatoid Arthritis and Lung Nodules.
作者: Matthew Koslow.;Sami M Bennji.;Stephanie Griffith-Richards.;Kareem Ahmad.;Geoffrey B Johnson.;Jay H Ryu.;Steven D Nathan.;Brian W Allwood.
来源: Chest. 2020年157卷5期e151-e155页
We present the case of a 48-year-old South African woman with no smoking history, and seropositive rheumatoid arthritis diagnosed in 2001. She was treated with chloroquine (150 mg, 4 times per week) and methotrexate (30 mg weekly) with well-controlled symptoms until 2015, when she developed a disease flare. Her treatment regimen was changed to leflunomide (20 mg daily) monotherapy with subsequent symptom control. Biologic agents were not accessible because of cost constraints.
4102. High-Dose Insulin Euglycemic Therapy in the Treatment of a Massive Caffeine Overdose.
A 33-year-old woman experienced 90 min of in-hospital cardiac arrest following an intentional overdose of anhydrous caffeine powder. In the face of prolonged and apparently futile resuscitation attempts, high-dose insulin euglycemic therapy was initiated. A loading dose of 1 IU/kg/h of IV insulin resulted in a dramatic improvement in perfusion. This was augmented by a 72-h infusion reaching a maximal rate of 10 IU/kg/h. The patient recovered full neurologic function and survived to discharge. Although high-dose insulin is effective in beta-blocker, calcium channel blocker, and tricyclic antidepressant overdose, this is seemingly the first description of its successful use in caffeine toxicity.
4110. A Molecular Classifier That Identifies Usual Interstitial Pneumonia in Transbronchial Biopsy Specimens of Patients With Interstitial Lung Disease.
作者: Ganesh Raghu.;Thomas V Colby.;Jeffrey L Myers.;Mark P Steele.;Sadia Benzaquen.;Karel Calero.;Amy H Case.;Gerard J Criner.;Steven D Nathan.;Navdeep S Rai.;Lars Hagmeyer.;J Russell Davis.;Sangeeta M Bhorade.;Giulia C Kennedy.;Umair A Gauher.;Fernando J Martinez.
来源: Chest. 2020年157卷5期1391-1392页 4112. The Strategic Establishment of Pulmonary and Critical Care Medicine as a Subspecialty in China: Third Report From the China-CHEST PCCM Fellowship Project.
作者: Renli Qiao.;Darcy D Marciniuk.;John D Buckley.;Stephanie M Levine.;Sinan Wu.;Chen Wang.
来源: Chest. 2020年157卷5期1082-1085页 |