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3963. In utero exposure to systemic antibiotics vs reference penicillins was not linked to congenital malformations.
Damkier P, Brønniche LM, Korch-Frandsen JF, Broe A. In utero exposure to antibiotics and risk of congenital malformations: a population-based study. Am J Obstet Gynecol. 2019;221:648.e1-648.e15. 31260651.
3964. In unprotected left main CAD, revascularization with PCI and DES increased risk for MACCE vs CABG at 5 years.
Holm NR, Mäkikallio T, Lindsay MM, et al. Percutaneous coronary angioplasty versus coronary artery bypass grafting in the treatment of unprotected left main stenosis: updated 5-year outcomes from the randomised, non-inferiority NOBLE trial. Lancet. 2019;395:191-9. 31879028.
3965. In acute HF, intensive and sustained vasodilation did not reduce a composite of death or HF readmission at 180 days.
Kozhuharov N, Goudev A, Flores D, et al. Effect of a strategy of comprehensive vasodilation vs usual care on mortality and heart failure rehospitalization among patients with acute heart failure: the GALACTIC randomized clinical trial. JAMA. 2019;322:2292-302. 31846016.
3966. In adults with AF who regularly drink alcohol, a 6-month abstinence intervention reduced AF recurrence and burden.
Voskoboinik A, Kalman JM, De Silva A, et al. Alcohol abstinence in drinkers with atrial fibrillation. N Engl J Med. 2020;382:20-8. 31893513.
3967. In irritable bowel syndrome, fecal microbiota transplantation improved symptoms at 3 months.
El-Salhy M, Hatlebakk JG, Gilja OH, Bråthen Kristoffersen A, Hausken T. Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut. 2020;69:859-67. 31852769.
3968. Supplementation with vitamin D plus calcium reduces fracture risk; vitamin D alone does not.
Yao P, Bennett D, Mafham M, et al. Vitamin D and calcium for the prevention of fracture: a systematic review and meta-analysis. JAMA Netw Open. 2019;2:e1917789. 31860103.
3970. In ischemic stroke with viable hypoperfused tissue, alteplase > 4.5 h after last seen well improves function.
Tsivgoulis G, Katsanos AH, Malhotra K, et al. Thrombolysis for acute ischemic stroke in the unwitnessed or extended therapeutic time window. Neurology. 2020;94:e1241-8. 31892636.
3976. Adding NT-proBNP to the Revised Cardiac Risk Index improved prediction of CV events after noncardiac surgery.
Duceppe E, Patel A, Chan MTV, et al. Preoperative N-terminal pro-B-type natriuretic peptide and cardiovascular events after noncardiac surgery: a cohort study. Ann Intern Med. 2020;172:96-104. 31869834.
3977. In older patients in the ED, higher ERA scores were associated with increased risk for mortality and return visits.
Espinoza Suarez NR, Walker LE, Jeffery MM, et al. Validation of the Elderly Risk Assessment index in the emergency department. Am J Emerg Med. 2019. [Epub ahead of print]. 31839521.
3978. In older adults with acute ischemic stroke, the Clinical Frailty Scale predicted mortality at 28 days.
Evans NR, Wall J, To B, et al. Clinical frailty independently predicts early mortality after ischaemic stroke. Age Ageing. 2020. [Epub ahead of print]. 31951248.
3979. Cytokine Levels in the Body Fluids of a Patient With COVID-19 and Acute Respiratory Distress Syndrome: A Case Report.
作者: Changsong Wang.;Kai Kang.;Yan Gao.;Ming Ye.;Xiuwen Lan.;Xueting Li.;Mingyan Zhao.;Kaijiang Yu.
来源: Ann Intern Med. 2020年173卷6期499-501页 3980. The New Normal: Key Considerations for Effective Serious Illness Communication Over Video or Telephone During the Coronavirus Disease 2019 (COVID-19) Pandemic.
In-person communication with patients hospitalized with COVID-19 and their families is often not possible. This article provides helpful guidance on how to have meaningful conversations about serious illness using telecommunication.
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