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3941. Tools to Promote Shared Decision-Making in Lung Cancer Screening Using Low-Dose CT Scanning: A Systematic Review.
作者: Mayuko Ito Fukunaga.;Kyle Halligan.;Jennifer Kodela.;Shaun Toomey.;Vanessa Fiorini Furtado.;Roger Luckmann.;Paul K J Han.;Kathleen M Mazor.;Sonal Singh.
来源: Chest. 2020年158卷6期2646-2657页
Decisions about lung cancer screening are inherently complex and create a need for methods to convey the risks and benefits of screening to patients.
3942. Association Between Nocturnal Hypoxemia and Cancer Incidence in Patients Investigated for OSA: Data From a Large Multicenter French Cohort.
作者: Grégoire Justeau.;Chloé Gervès-Pinquié.;Marc Le Vaillant.;Wojciech Trzepizur.;Nicole Meslier.;François Goupil.;Thierry Pigeanne.;Sandrine Launois.;Laurene Leclair-Visonneau.;Philippe Masson.;Acya Bizieux-Thaminy.;Marie-Pierre Humeau.;Christelle Gosselin.;Margaux Blanchard.;Thierry Urban.;Frédéric Gagnadoux.; .
来源: Chest. 2020年158卷6期2610-2620页
Previous studies have yielded inconsistent findings regarding the association between OSA and cancer in humans.
3943. Effect of Antiviral Therapy on the Outcome of Mechanically Ventilated Patients With Herpes Simplex Virus Type 1 in BAL Fluid: A Retrospective Cohort Study.
作者: Elisabeth Heimes.;Michael Baier.;Christina Forstner.;Sebastian Weis.;Michael Bauer.;Michael Fritzenwanger.;André Scherag.;Mathias W Pletz.;Miriam Kesselmeier.;Stefan Hagel.
来源: Chest. 2020年158卷5期1867-1875页
Herpes simplex virus type 1 (HSV-1) is frequently detected in the BAL fluid of patients on mechanical ventilation.
3944. Mixed Venous Oxygen Saturation Is a Better Prognosticator Than Cardiac Index in Pulmonary Arterial Hypertension.
作者: Ghaleb Khirfan.;Allaa Almoushref.;Tawfeq Naal.;Batool Abuhalimeh.;Raed A Dweik.;Gustavo A Heresi.;Adriano R Tonelli.
来源: Chest. 2020年158卷6期2546-2555页
European Society of Cardiology (ESC) and European Respiratory Society (ERS) guidelines include thermodilution cardiac index (TDCI) and mixed venous oxygen saturation (SvO2) as two of the three hemodynamic determinations used in risk assessment of patients with pulmonary arterial hypertension (PAH). SvO2 may be a better measurement than TDCI to assess prognosis in patients with either idiopathic or heritable PAH.
3945. WITHDRAWN: Clinical and Genetic Spectrum of Children with Primary Ciliary Dyskinesia in China.
作者: Yuhong Guan.;Haiming Yang.;Xingfeng Yao.;Hui Xu.;Hui Liu.;Xiaolei Tang.;Chanjuan Hao.;Xiang Zhang.;Shunying Zhao.;Wentong Ge.;Xin Ni.
来源: Chest. 2020年 3946. Systemic Capillary Leak Syndrome Secondary to Coronavirus Disease 2019.
作者: Robert Case.;Aliaksandr Ramaniuk.;Pamela Martin.;Paul J Simpson.;Christopher Harden.;Ali Ataya.
来源: Chest. 2020年158卷6期e267-e268页
Systemic capillary leak syndrome is a rare disorder characterized by dysfunctional inflammatory response, endothelial dysfunction, and extravasation of fluid from the vascular space to the interstitial space leading to shock, hemoconcentration, hypoalbuminemia, and subsequent organ failure. The condition may be idiopathic or secondary to an underlying cause, which can include viral infections. Here we describe a patient with acute coronavirus disease 2019 (COVID-19) infection who presented with hemoconcentration, shock, and hypoalbuminemia. The patient subsequently developed rhabdomyolysis and compartment syndrome of all four extremities, requiring fasciotomies. This is the first reported case of systemic capillary leak syndrome associated with COVID-19 infection. This case adds to the evolving spectrum of inflammatory effects associated with this viral infection.
3947. Development of Learning Curves for Bronchoscopy: Results of a Multicenter Study of Pulmonary Trainees.
作者: Nha Voduc.;Rosemary Adamson.;Alia Kashgari.;Mark Fenton.;Nancy Porhownick.;Margaret Wojnar.;Krishna Sharma.;Ashley-Mae Gillson.;Carol Chung.;Meghan McConnell.
来源: Chest. 2020年158卷6期2485-2492页
There are currently no reference standards for the development of competence in bronchoscopy.
3948. BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic Fibrosis.
作者: Alya Ishak.;Stephen M Stick.;Lidija Turkovic.;Sarath C Ranganathan.;Louise King.;Joanne Harrison.;Peter D Sly.;Daan Caudri.;André Schultz.; .
来源: Chest. 2020年158卷6期2314-2322页
Pulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity.
3949. Airway Clearance Techniques in Bronchiectasis: Analysis From the United States Bronchiectasis and Non-TB Mycobacteria Research Registry.
作者: Ashwin Basavaraj.;Radmila Choate.;Doreen Addrizzo-Harris.;Timothy R Aksamit.;Alan Barker.;Charles L Daley.;M Leigh Anne Daniels.;Edward Eden.;Angela DiMango.;Kevin Fennelly.;David E Griffith.;Margaret M Johnson.;Michael R Knowles.;Mark L Metersky.;Peadar G Noone.;Anne E O'Donnell.;Kenneth N Olivier.;Matthias A Salathe.;Andreas Schmid.;Byron Thomashow.;Gregory Tino.;Kevin L Winthrop.
来源: Chest. 2020年158卷4期1376-1384页
In patients with bronchiectasis, airway clearance techniques (ACTs) are important management strategies.
3950. Two Immunocompromised Patients With Diffuse Alveolar Hemorrhage as a Complication of Severe Coronavirus Disease 2019.
作者: Christian Löffler.;Juliane Mahrhold.;Peter Fogarassy.;Martin Beyer.;Bernhard Hellmich.
来源: Chest. 2020年158卷5期e215-e219页
Diffuse alveolar hemorrhage (DAH) is a severe and potentially life-threatening disease manifestation. In addition to autoimmune diseases such as antineutrophil cytoplasmic antibody-associated vasculitis and anti-glomerular basement membrane syndrome, pulmonary viral infections are known to be culprits of DAH. Health-care providers worldwide in the coronavirus disease 2019 pandemic have been confronted with an unprecedented number of viral lung infections, with great variance in symptoms and severity. Hemoptysis, the key symptom of DAH, is a rare complication. We present two cases of immunocompromised patients with rapidly developing hypoxemic respiratory failure and evidence of DAH in the context of severe acute respiratory syndrome coronavirus 2 infection.
3953. Mechanisms of Exercise Limitation and Prevalence of Pulmonary Hypertension in Pulmonary Langerhans Cell Histiocytosis.
作者: Glaucia Itamaro Heiden.;Juliana Barbosa Sobral.;Carolina Salim Gonçalves Freitas.;André Luis Pereira de Albuquerque.;João Marcos Salge.;Ronaldo Adib Kairalla.;Caio Júlio César Dos Santos Fernandes.;Carlos Roberto Ribeiro Carvalho.;Rogério Souza.;Bruno Guedes Baldi.
来源: Chest. 2020年158卷6期2440-2448页
Pulmonary Langerhans cell histiocytosis (PLCH) determines reduced exercise capacity. The speculated mechanisms of exercise impairment in PLCH are ventilatory and cardiocirculatory limitations, including pulmonary hypertension (PH).
3954. PROPHETIC: Prospective Identification of Pneumonia in Hospitalized Patients in the ICU.
作者: Stephen P Bergin.;Adrian Coles.;Sara B Calvert.;John Farley.;John H Powers.;Marcus J Zervos.;Matthew Sims.;Marin H Kollef.;Michael J Durkin.;Badih A Kabchi.;Helen K Donnelly.;Ana Cecilia Bardossy.;Claire Greenshields.;Daniel Rubin.;Jie-Lena Sun.;Karen Chiswell.;Jonas Santiago.;Peidi Gu.;Pamela Tenaerts.;Vance G Fowler.;Thomas L Holland.
来源: Chest. 2020年158卷6期2370-2380页
Pneumonia is the leading infection-related cause of death. The use of simple clinical criteria and contemporary epidemiology to identify patients at high risk of nosocomial pneumonia should enhance prevention efforts and facilitate development of new treatments in clinical trials.
3955. High-Flow Nasal Cannula in the Immediate Postoperative Period: A Systematic Review and Meta-analysis.
作者: Dipayan Chaudhuri.;David Granton.;Dominic Xiang Wang.;Karen E A Burns.;Yigal Helviz.;Sharon Einav.;Vatsal Trivedi.;Tommaso Mauri.;Jean-Damien Ricard.;Jordi Mancebo.;Jean-Pierre Frat.;Sameer Jog.;Gonzalo Hernandez.;Salvatore M Maggiore.;Lawrence Mbuagbaw.;Carol L Hodgson.;Samir Jaber.;Ewan C Goligher.;Laurent Brochard.;Bram Rochwerg.
来源: Chest. 2020年158卷5期1934-1946页
Studies have demonstrated that high-flow nasal cannula (HFNC) prevents intubation in acute hypoxic respiratory failure when compared with conventional oxygen therapy (COT). However, the data examining routine HFNC use in the immediate postoperative period are less clear.
3956. Deterioration of Nighttime Respiratory Mechanics in COPD: Impact of Bronchodilator Therapy.
作者: Nicolle J Domnik.;Matthew D James.;Robin E Scheeren.;Grace A Ayoo.;Sarah M Taylor.;Amanda T Di Luch.;Kathryn M Milne.;Sandra G Vincent.;Devin B Phillips.;Amany F Elbehairy.;Sophie J Crinion.;Helen S Driver.;J Alberto Neder.;Denis E O'Donnell.
来源: Chest. 2021年159卷1期116-127页
COPD is associated with nighttime respiratory symptoms, poor sleep quality, and increased risk of nocturnal death. Overnight deterioration of inspiratory capacity (IC) and FEV1 have been documented previously. However, the precise nature of this deterioration and mechanisms by which evening bronchodilation may mitigate this occurrence have not been studied.
3957. Association of Cigarette Type and Nicotine Dependence in Patients Presenting for Lung Cancer Screening.
作者: Nichole T Tanner.;Nina A Thomas.;Ralph Ward.;Alana Rojewski.;Mulugeta Gebregziabher.;Benjamin A Toll.;Gerard A Silvestri.
来源: Chest. 2020年158卷5期2184-2191页
Over decades, there have been several alterations to cigarettes, including the addition of filters and flavoring. However, lung cancer remains the leading cause of cancer-related death in the United States.
3960. Coinfection With Multiple Nontuberculous Mycobacteria as a Possible Exacerbating Factor in Pulmonary Nontuberculous Mycobacteriosis: Clone Library Analysis Using the 16S Ribosomal RNA Gene.
作者: Keisuke Naito.;Shingo Noguchi.;Kazuhiro Yatera.;Toshinori Kawanami.;Kei Yamasaki.;Kazumasa Fukuda.;Hiroaki Ikegami.;Kentaro Akata.;Takashi Kido.;Noriho Sakamoto.;Mitsumasa Saito.;Hiroshi Mukae.
来源: Chest. 2020年158卷6期2304-2313页
Mycobacterial culture is the gold standard for the diagnosis of nontuberculous Mycobacterium (NTM) infections. However, this method is not suitable for detection of coinfection with different NTMs.
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