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共有 3485 条符合本次的查询结果, 用时 24.7402169 秒

3141. Seeing a cause for blindness in severe pancreatitis.

作者: A D Hopper.;D Gosling.;S Patwary.;D Partridge.;M Peterson.
来源: Gut. 2016年65卷1期32, 46页

3142. Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer.

作者: Lixia Xu.;Xiaoxing Li.;Muyan Cai.;Jinna Chen.;Xiangchun Li.;William K K Wu.;Wei Kang.;Joanna Tong.;Ka-Fai To.;Xin-Yuan Guan.;Joseph J Y Sung.;Francis K L Chan.;Jun Yu.
来源: Gut. 2016年65卷4期635-46页
Using whole genome sequencing, we identified gene amplification of solute carrier family 12 member 5 (SLC12A5) located at 20q13.12 in colorectal cancer (CRC). We analysed its amplification, overexpression, biological effects and prognostic significance in CRC.

3143. Reliability among central readers in the evaluation of endoscopic findings from patients with Crohn's disease.

作者: Reena Khanna.;Guangyong Zou.;Geert D'Haens.;Paul Rutgeerts.;J W D McDonald.;Marco Daperno.;Brian G Feagan.;William J Sandborn.;Elena Dubcenco.;Larry Stitt.;Margaret K Vandervoort.;Allan Donner.;Allison Luo.;Barrett G Levesque.
来源: Gut. 2016年65卷7期1119-25页
The Crohn's Disease Endoscopic Index of Severity (CDEIS) and Simple Endoscopic Score for Crohn's Disease (SES-CD) are commonly used to assess Crohn's disease (CD) activity; however, neither instrument has been fully validated. We assessed intra-rater and inter-rater reliability of these indices.

3144. The applicability of hepatocellular carcinoma risk prediction scores in a North American patient population with chronic hepatitis B infection.

作者: Mahmoud Abu-Amara.;Orlando Cerocchi.;Gurtej Malhi.;Suraj Sharma.;Colina Yim.;Hemant Shah.;David K Wong.;Harry L A Janssen.;Jordan J Feld.
来源: Gut. 2016年65卷8期1347-58页
Patients with chronic hepatitis B (CHB) infection are at an increased risk of developing hepatocellular carcinoma (HCC). Risk scores have been developed in Asian populations to predict HCC risk over time.

3145. Clinical response to peroral endoscopic myotomy in patients with idiopathic achalasia at a minimum follow-up of 2 years.

作者: Yuki B Werner.;Guido Costamagna.;Lee L Swanström.;Daniel von Renteln.;Pietro Familiari.;Ahmed M Sharata.;Tania Noder.;Guido Schachschal.;Jan F Kersten.;Thomas Rösch.
来源: Gut. 2016年65卷6期899-906页
The recently developed technique for peroral endoscopic myotomy (POEM) has been shown to be effective in several short-term studies. Longer term outcome data are largely non-existent.

3146. Impact of surveillance for Barrett's oesophagus on tumour stage and survival of patients with neoplastic progression.

作者: F Kastelein.;S H van Olphen.;E W Steyerberg.;M C W Spaander.;M J Bruno.; .
来源: Gut. 2016年65卷4期548-54页
Endoscopic surveillance for Barrett's oesophagus (BO) is under discussion given the overall low incidence of neoplastic progression and lack of evidence that it prevents advanced oesophageal adenocarcinoma (OAC). The aim of this study was to evaluate the impact of endoscopic BO surveillance on tumour stage and survival of patients with neoplastic progression.

3147. Cross-immunogenicity: antibodies to infliximab in Remicade-treated patients with IBD similarly recognise the biosimilar Remsima.

作者: Shomron Ben-Horin.;Miri Yavzori.;Itai Benhar.;Ella Fudim.;Orit Picard.;Bella Ungar.;SooYoung Lee.;SungHwan Kim.;Rami Eliakim.;Yehuda Chowers.
来源: Gut. 2016年65卷7期1132-8页
The cross-immunogenicity of the recently approved infliximab-biosimilar Remsima (CT-P13) with the originator drug Remicade is still unknown.

3148. Identification and genetic manipulation of human and mouse oesophageal stem cells.

作者: Youngtae Jeong.;Horace Rhee.;Shanique Martin.;Daniel Klass.;Yuan Lin.;Le Xuan Truong Nguyen.;Weiguo Feng.;Maximilian Diehn.
来源: Gut. 2016年65卷7期1077-86页
Human oesophageal stem cell research is hampered by the lack of an optimal assay system to study self-renewal and differentiation. We aimed to identify and characterise human and mouse oesophageal stem/progenitor cells by establishing 3-dimensional organotypic sphere culture systems for both species.

3149. Gastroenterology training in Europe: unmet educational needs beyond the machines.

作者: Gianluca Ianiro.;Antonio Gasbarrini.
来源: Gut. 2016年65卷1期185-7页

3150. The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.

作者: Michele Cioffi.;Sara M Trabulo.;Yolanda Sanchez-Ripoll.;Irene Miranda-Lorenzo.;Enza Lonardo.;Jorge Dorado.;Catarina Reis Vieira.;Juan Carlos Ramirez.;Manuel Hidalgo.;Alexandra Aicher.;Stephan Hahn.;Bruno Sainz.;Christopher Heeschen.
来源: Gut. 2015年64卷12期1936-48页
Cancer stem cells (CSCs) represent the root of many solid cancers including pancreatic ductal adenocarcinoma, are highly chemoresistant and represent the cellular source for disease relapse. However the mechanisms involved in these processes still need to be fully elucidated. Understanding the mechanisms implicated in chemoresistance and metastasis of pancreatic cancer is critical to improving patient outcomes.

3151. U.K. guidelines on the management of variceal haemorrhage in cirrhotic patients.

作者: Dhiraj Tripathi.;Adrian J Stanley.;Peter C Hayes.;David Patch.;Charles Millson.;Homoyon Mehrzad.;Andrew Austin.;James W Ferguson.;Simon P Olliff.;Mark Hudson.;John M Christie.; .
来源: Gut. 2015年64卷11期1680-704页
These updated guidelines on the management of variceal haemorrhage have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines which this document supersedes were written in 2000 and have undergone extensive revision by 13 members of the Guidelines Development Group (GDG). The GDG comprises elected members of the BSG liver section, representation from British Association for the Study of the Liver (BASL) and Liver QuEST, a nursing representative and a patient representative. The quality of evidence and grading of recommendations was appraised using the AGREE II tool.The nature of variceal haemorrhage in cirrhotic patients with its complex range of complications makes rigid guidelines inappropriate. These guidelines deal specifically with the management of varices in patients with cirrhosis under the following subheadings: (1) primary prophylaxis; (2) acute variceal haemorrhage; (3) secondary prophylaxis of variceal haemorrhage; and (4) gastric varices. They are not designed to deal with (1) the management of the underlying liver disease; (2) the management of variceal haemorrhage in children; or (3) variceal haemorrhage from other aetiological conditions.

3152. Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence.

作者: Monika Schaubeck.;Thomas Clavel.;Jelena Calasan.;Ilias Lagkouvardos.;Sven Bastiaan Haange.;Nico Jehmlich.;Marijana Basic.;Aline Dupont.;Mathias Hornef.;Martin von Bergen.;André Bleich.;Dirk Haller.
来源: Gut. 2016年65卷2期225-37页
Dysbiosis of the intestinal microbiota is associated with Crohn's disease (CD). Functional evidence for a causal role of bacteria in the development of chronic small intestinal inflammation is lacking. Similar to human pathology, TNF(deltaARE) mice develop a tumour necrosis factor (TNF)-driven CD-like transmural inflammation with predominant ileal involvement.

3153. Immunogenicity to infliximab is associated with HLA-DRB1.

作者: Thomas Billiet.;Niels Vande Casteele.;Thomas Van Stappen.;Fred Princen.;Sharat Singh.;Ann Gils.;Marc Ferrante.;Gert Van Assche.;Isabelle Cleynen.;Severine Vermeire.
来源: Gut. 2015年64卷8期1344-5页

3154. Efficacy of mesalazine in IBS.

作者: Thazin Min.;Alexander C Ford.
来源: Gut. 2016年65卷1期187-8页

3155. Reliability and agreement studies: a guide for clinical investigators.

作者: Ruben Hernaez.
来源: Gut. 2015年64卷7期1018-27页

3156. Screening diabetic patients for non-alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: a prospective cohort study.

作者: Raymond Kwok.;Kai Chow Choi.;Grace Lai-Hung Wong.;Yuying Zhang.;Henry Lik-Yuen Chan.;Andrea On-Yan Luk.;Sally She-Ting Shu.;Anthony Wing-Hung Chan.;Ming-Wai Yeung.;Juliana Chung-Ngor Chan.;Alice Pik-Shan Kong.;Vincent Wai-Sun Wong.
来源: Gut. 2016年65卷8期1359-68页
Type 2 diabetes is an important risk factor for non-alcoholic fatty liver disease (NAFLD), but current guidelines provide conflicting recommendations on whether diabetic patients should be screened for NAFLD. We therefore studied the strategy of screening diabetic patients by FibroScan.

3157. Detection of precancerous gastric lesions and gastric cancer through exhaled breath.

作者: Haitham Amal.;Marcis Leja.;Konrads Funka.;Roberts Skapars.;Armands Sivins.;Guntis Ancans.;Inta Liepniece-Karele.;Ilze Kikuste.;Ieva Lasina.;Hossam Haick.
来源: Gut. 2016年65卷3期400-7页
Timely detection of gastric cancer (GC) and the related precancerous lesions could provide a tool for decreasing both cancer mortality and incidence.

3158. Antibodies to adalimumab are associated with future inflammation in Crohn's patients receiving maintenance adalimumab therapy: a post hoc analysis of the Karmiris trial.

作者: Filip Baert.;Venkateswarlu Kondragunta.;Steven Lockton.;Niels Vande Casteele.;Scott Hauenstein.;Sharat Singh.;Konstantinos Karmiris.;Marc Ferrante.;Ann Gils.;Séverine Vermeire.
来源: Gut. 2016年65卷7期1126-31页
Data on immunogenicity to adalimumab (ADL) therapy in patients with IBD is limited. We performed additional analyses on the Karmiris cohort using the homogeneous mobility shift assay (HMSA) focusing on the inter-relationship of serum ADL concentration, antibodies-to-adalimumab (ATA), inflammatory markers and sustained response.

3159. Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities.

作者: Charlotte Hedin.;Christopher J van der Gast.;Geraint B Rogers.;Leah Cuthbertson.;Sara McCartney.;Andrew J Stagg.;James O Lindsay.;Kevin Whelan.
来源: Gut. 2016年65卷6期944-53页
To determine the existence of mucosal dysbiosis in siblings of patients with Crohn's disease (CD) using 454 pyrosequencing and to comprehensively characterise and determine the influence of genotypical and phenotypical factors, on that dysbiosis. Siblings of patients with CD have elevated risk of developing CD and display aspects of disease phenotype, including faecal dysbiosis. Whether the mucosal microbiota is disrupted in these at-risk individuals is unknown.

3160. Stimulating hepatocyte renewal: a new paradigm for the treatment of severe alcoholic hepatitis unresponsive to corticosteroids?

作者: Richard Moreau.
来源: Gut. 2015年64卷12期1839-40页
共有 3485 条符合本次的查询结果, 用时 24.7402169 秒