291. Bedaquiline Activity against Leprosy.
作者: Abdoulaye Fomba.;Fadima C Haidara.;Mamoudou Kodio.;Catherine Arama.;Emmanuelle Cambau.;Aurélie Chauffour.;Nicolas Veziris.;Bettina E Broeckling.;Alaine K Warren.;Bertrand Cauchoix.;Alexandre Alcaïs.;Laurent Marsollier.;Henri Assé.;Mary Jackson.;Samba Ousmane Sow.;Ousmane Faye.;Vincent Jarlier.;Stewart T Cole.;Charlotte Avanzi.;Alexandra Aubry.;Roch C Johnson.
来源: N Engl J Med. 2025年392卷21期2174-2176页 298. A Trial of Trimethoprim-Sulfamethoxazole in Pregnancy to Improve Birth Outcomes.
作者: Bernard Chasekwa.;Fortunate Munhanzi.;Lenin Madhuyu.;Gabriel Mbewe.;Vincent Mabika.;Dzivaidzo Chidhanguro.;Tendai Kofi.;Jonthan Munengiwa.;Hilda Mapfumo.;Mercy Musapa.;Sipho Shumba.;Elizabeth Hungwe.;Mary Nhokwara.;Nester Bushe.;Rudo Kufa.;Phatisiwe Mazula.;Muchaneta Chikombingo.;Alice Tengende.;Admire Zanga.;Asaph Ziruma.;Tsitsi Bere.;Success Munyengwa.;Charity Mudimbu.;Zvikomborero Murwira.;Shepherd Mudzingwa.;Eddington Mpofu.;Batsirai Mutasa.;Virginia Sauramba.;Elisha Masakadze.;Thompson Runodamoto.;Courage Chiorera.;Alfred Mushininga.;Claire D Bourke.;Ruairi C Robertson.;Jeniffer Perussolo.;Nikos Donos.;Chandiwana Nyachowe.;Mary Muchekeza.;Jefrey Chikunya.;Melanie Smuk.;Kuda Mutasa.;Naume V Tavengwa.;Lisa L Langhaug.;Robert Ntozini.;Stephen P Munjanja.;Andrew J Prendergast.
来源: N Engl J Med. 2025年392卷21期2125-2134页
Maternal infections underlie several adverse birth outcomes. Whether trimethoprim-sulfamethoxazole prophylaxis during pregnancy will improve birth outcomes is unknown.
299. Omitting Regional Nodal Irradiation after Response to Neoadjuvant Chemotherapy.
作者: Eleftherios P Mamounas.;Hanna Bandos.;Julia R White.;Thomas B Julian.;Atif J Khan.;Simona F Shaitelman.;Mylin A Torres.;Frank A Vicini.;Patricia A Ganz.;Susan A McCloskey.;Peter C Lucas.;Nilendu Gupta.;X Allen Li.;Beryl McCormick.;Benjamin Smith.;Rahul D Tendulkar.;Vivek S Kavadi.;Koji Matsumoto.;Samantha Andrews Seaward.;William J Irvin.;Jolinta Y Lin.;Robert W Mutter.;Thierry M Muanza.;Jannifer Stromberg.;Reshma Jagsi.;Anna C Weiss.;Walter J Curran.;Norman Wolmark.
来源: N Engl J Med. 2025年392卷21期2113-2124页
The benefit of regional nodal irradiation in the treatment of breast cancer is well established for patients with pathologically positive axillary nodes, but whether it is also beneficial for patients whose nodes become pathologically tumor free (ypN0) after neoadjuvant chemotherapy remains unclear.
300. Corynebacterium diphtheriae Outbreak in Migrant Populations in Europe.
作者: Andreas Hoefer.;Helena Seth-Smith.;Federica Palma.;Stefanie Schindler.;Luca Freschi.;Alexandra Dangel.;Anja Berger.;Joshua D'Aeth.;Rebecca Cordery.;Enrique Delgado-Rodriguez.;Eva Gruner.;Domenica Flury.;Vladimira Hinic.;Julian Kofler.;Reto Lienhard.;Rob Mariman.;Oliver Nolte.;Adrian Schibli.;Julie Toubiana.;Marianna Traugott.;Stephanie Jacquinet.;Alexander Indra.;Norman K Fry.;Daniel Palm.;Andreas Sing.;Sylvain Brisse.;Adrian Egli.; .
来源: N Engl J Med. 2025年392卷23期2334-2345页
A surge of cases of Corynebacterium diphtheriae infection was observed in reception centers for migrants in Europe beginning in the summer of 2022. Most of the cases were cutaneous, although some respiratory cases as well as one death were reported. A pan-European consortium was created to assess the clinical, epidemiologic, and microbiologic features of this outbreak.
|