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1. Clinical Outcomes in Chronic Obstructive Pulmonary Disease Patients with Disease Stability: Data from the KOCOSS Cohort.
作者: Eunjeong Son.;Hyewon Seo.;Seung Won Ra.;Seoung Ju Park.;Soo-Jung Um.;Seong Yong Lim.;Hyoung Kyu Yoon.;Kwang Ha Yoo.;Joon Young Choi.;Chin Kook Rhee.
来源: Chest. 2025年
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with progressive airflow limitation. Despite therapeutic advances, current treatments poorly halt COPD progression. Disease stability (DS) is a proposed treatment goal, but its clinical significance remains uncertain.
3. Adjunctive Corticosteroid Use and Clinical Outcomes in Non-HIV Pneumocystis jirovecii Pneumonia.
作者: Aaron M Pulsipher.;Holenarasipur R Vikram.;Michael B Gotway.;Rodrigo Cartin-Ceba.;Emily R Thompson.;Andrew H Limper.;Ayan Sen.;Augustine Lee.;Kealy Ham.
来源: Chest. 2025年
Adjunctive corticosteroids improve outcomes in HIV-associated Pneumocystis jirovecii pneumonia (PCP), but their role in non-HIV patients is uncertain. Prior evidence has largely been limited to binary treatment groups and has rarely accounted for daily or cumulative dose effects.
4. Geographical variations in continuous positive airway pressure termination rates in patients with obstructive sleep apnea: insights from the ALASKA French nationwide dataset.
作者: Sébastien Bailly.;Guillaume Deltreil.;Florent Lavergne.;Renaud Tamisier.;Sébastien Baillieul.;Jean Louis Pépin.
来源: Chest. 2025年 5. Examining the threat of H5N1 highly pathogenic avian influenza to human health.
作者: Juliette Blais-Savoie.;Emily Halajian.;Kuganya Nirmalarajah.;Andra Banete.;Juan C Corredor.;Jonathon D Kotwa.;Yaejin Lee.;Sugandha Raj.;Shayan Sharif.;Nicole Mideo.;Samira Mubareka.
来源: Chest. 2025年 6. Growth Differentiation Factor-15 Improves Prognostic Accuracy of Risk Stratification in Pulmonary Arterial Hypertension.
作者: An-Yi Wang.;Jie-Ling Ma.;Yue Cui.;Bao-Chen Qiu.;Chao Liu.;Dan Lu.;Yin-Jian Yang.;Yu-Ping Zhou.;Ze-Jian Zhang.;Xi-Qi Xu.;Xin Jiang.;Tian-Yu Lian.;Chun-Yan Cheng.;Kai Sun.;Pei-Wen Wang.;Yue-Jiao Ma.;Zhi-Cheng Jing.
来源: Chest. 2025年
The etiology of pulmonary arterial hypertension (PAH) is complex and the risk is heterogeneous. Growth differentiation factor-15 (GDF-15) has been reported to be associated with the prognosis of patients with PAH, but whether the use of GDF-15 as an additional prognostic biomarker can improve pre-existing PAH risk stratification remains unclear.
7. A National Evaluation of Intercostal Chest Drain Removal Strategies.
作者: Author List Niki Veale.;Anthony W Martinelli.;Dheeraj Sethi.;Phillip De Souza.;Khaing Zar Mon.;Joyce Oi Suet Cheng.;David Morrow.;May Sam.;Irfan Saleem.;Kay Por Yip.;Jennifer Kerks.;David E Henshall.;Tobias Smitherman-Cairns.;Katherine Smith.;Daniel Mitchell.;Karl Jackson.;Benjamin Pippard.;Seemab Paul.;Waheed Mohammad.;James Hyman.;Ben Rowlands.;Samantha Bosence.;Catharine Pearce.;Ben Probyn.;Richard Thorley.;Matthew Mitchell.;Andrew Griffiths.;Richard Westley.;Abdullah Huda.;Asim Mehmood.;Abid Khan.;Vern Tee.;Rachel Crooks.;Paul Minnis.;Lewis Standing.;Wei Hann Ong.;M Salman Rashid.;Ahmed Salih.;Eve Lynn Koh.;Ching Khai Ho.;Yiwen Soo.;Matthew Hayes.;Clodagh Holmes.;Fatima Al-Arrayed.;Abeer Saad.;Beenish Iqbal.;Sam Trewick.;Patrick Goodley.;Jonathan Oldershaw.;Elizabeth Thompson.;Alexandra Hodge.;Mohamed Gadallah.;Rahul Bhat.;Eleanor Barton.;Anand Sundaralingam.;Osei Kankam.;James Quinn.;John P Corcoran.;Steven P Walker.;Avinash Aujayeb.;Jurgen Herre.;Akhilesh Jha.;Stefan J Marciniak.;Najib M Rahman.;Rob J Hallifax.
来源: Chest. 2025年
Management of spontaneous pneumothorax often involves intercostal chest drain (ICD) insertion. Determining when to remove the ICD is controversial, with significant variation in practice. Establishing optimal ICD management in pneumothorax could reduce morbidity and improve cost effectiveness.
9. Impact of Elevated Pulmonary Arterial Wedge Pressure on Safety and Efficacy of Balloon Pulmonary Angioplasty in the Treatment of Chronic Thromboembolic Pulmonary Hypertension.
作者: Piotr Szwed.;Paweł Kurzyna.;Marta Banaszkiewicz-Cyganik.;Piotr Kędzierski.;Michał Łomiak.;Rafał Wolański.;Marcin Wasilewski.;Michał Florczyk.;Michał Piłka.;Adam Torbicki.;Marcin Kurzyna.;Szymon Darocha.
来源: Chest. 2025年
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare condition caused by thromboembolic occlusions of the pulmonary arteries and characterized by elevated pulmonary pressure, vascular remodelling, and right ventricular overload, which can be treated effectively with balloon pulmonary angioplasty (BPA). The study aimed to evaluate whether elevated pulmonary arterial wedge pressure (PAWP), associated with left ventricular dysfunction, influences the effectiveness and safety of BPA treatment.
10. Post-ICU Care Trajectories and Outcomes Among Veterans: Comparing VA and Community Hospital Discharges.
作者: Zachary Hahn.;Hiam Naiditch.;Martha F Brucato.;Victor Talisa.;Brian Tyler.;John R Hotchkiss.;Sachin Yende.;Bryan J McVerry.;Florian B Mayr.
来源: Chest. 2025年
Critical illness survivors face fragmented care transitions, leading to readmissions, emergency care use, and death. The Veterans Affairs Patient Aligned Care Team model emphasizes coordinated outpatient follow-up, yet many veterans now receive VA-purchased intensive care at community hospitals, potentially disrupting continuity.
11. Relationship between Framingham 10-year cardiovascular disease risk score and pulse wave amplitude drop characteristics in a sleep clinic cohort.
作者: Glenn M Stewart.;Benjamin K Tong.;Philip deChazal.;Joanne Flood.;Yu Sun Bin.;Kristina Kairaitis.;John R Wheatley.;Andrew S L Chan.;Amanda J Piper.;Brendon J Yee.;Peter A Cistulli.; .
来源: Chest. 2025年
Pulse oximetry-derived measures of autonomic vascular re-activity during sleep - quantified by pulse wave amplitude drop (PWAD) characteristics such as PWAD index - have recently been proposed as a biomarker of cardiovascular disease (CVD) outcomes in patients with obstructive sleep apnea (OSA).
12. Serial MRI Measures Short-term Parenchymal Changes in Neonatal Bronchopulmonary Dysplasia.
作者: Samal Munidasa.;Nara S Higano.;Matthew M Willmering.;Abdullah S Bdaiwi.;Xavier Hoyos Cordon.;Daniela Bullard Elias.;Robert J Fleck.;Paul S Kingma.;Erik B Hysinger.;Jason C Woods.
来源: Chest. 2025年
Bronchopulmonary dysplasia (BPD) is the most common neonatal lung parenchymal disease characterized by obstructive and restrictive lung abnormalities. Evaluation of neonatal BPD lung disease using MRI has been shown to be more sensitive to short-term outcomes than standard clinical measures. However, the longitudinal trajectory of parenchymal disease remains poorly characterized.
13. Cardiovascular Events in COPD: Complementary Role of Cardiac Risk and Coronary Artery Calcium Scores.
作者: Juan P de-Torres.;Ciro Casanova.;Jorge Zagaceta.;José M Marín.;Carlos Cabrera.;Ana Ezponda.;Arantza Campo.;Ana Belén Alcaide.;Luis Seijo.;Gorka Bastarrika.;Victor Pinto-Plata.;Miguel Divo.;Bartolome R Celli.
来源: Chest. 2025年
Patients with COPD are at high risk of major adverse cardiovascular events (MACEs) developing. Existing clinical tools for risk stratification in these patients have underperformed in predicting the outcomes.
14. Hypoglossal Nerve Stimulation in the Context of non-Continuous Positive Airway Pressure Therapy in Patients with Obstructive Sleep Apnea: Improvement in the Apnea-Hypopnea Index in Randomized Controlled Trials.15. Long-Term Major Respiratory Mortality Among 5-Year Survivors of Adolescent and Young Adult Cancer.
Adolescent and young adults (AYAs) diagnosed with cancer are at risk of experiencing pulmonary dysfunction years or even decades following completion of treatment.
17. Clinical Validation of a Multidimensional Diagnostic Approach for Chronic Obstructive Pulmonary Disease in Chinese.
作者: Fan Wu.;Suyin Huang.;Kunning Zhou.;Tingting Xia.;Qi Wan.;Gaoying Tang.;Zhishan Deng.;Youlan Zheng.;Ningning Zhao.;Heshen Tian.;Cuiqiong Dai.;Lifei Lu.;Xiaohui Wu.;Zihui Wang.;Xiaoyan Huang.;Xiaohuan Pan.;Jian Zhang.;Xianliang Zeng.;Zhifeng Gao.;Changli Yang.;Shengtang Chen.;Yongqing Huang.;Shuqing Yu.;Erkang Yi.;Yu Deng.;Surya P Bhatt.;Yumin Zhou.;Pixin Ran.; .
来源: Chest. 2025年
Although spirometry is used to diagnose COPD, a new multidimensional diagnostic schema has been recently proposed to diagnose this disease. However, evidence in Chinese individuals and never smokers is limited.
18. Comparative outcomes and side effects of immunosuppressants and tumor necrosis factor inhibitors in sarcoidosis: a real-world data analysis.
Sarcoidosis is a complex systemic granulomatous disease with varying clinical manifestations, and immunosuppressive agents and tumor necrosis factor (TNF) inhibitors have been used in severe and refractory cases. However, the comparison of the serious side effects of these treatments remains poorly understood.
19. Pleural Manometry in Pneumothorax: Evaluating Tension Physiology and Predicting Outcomes.
作者: Ardian Latifi.;Dylan Wang.;Elliot D Backer.;Nagendra Madisi.;Amit Chopra.;Christopher M Kapp.;Max Wayne.;John Howe.;Cheryl Pai.;Lonny Yarmus.;David Feller-Kopman.;Jeffrey Thiboutot.
来源: Chest. 2025年
Tension pneumothorax (TP) traditionally is defined pleural pressure (Ppl) exceeding atmospheric pressure, which reduces venous return and leads to hemodynamic collapse. However, Ppl has yet to be measured directly in TP because of technical limitations, nor has it been studied in predicting outcomes for pneumothorax.
20. Post-Intensive Care Syndrome Awareness and Communication: Surveys of ICU Providers and Patients.
作者: Mark L Rolfsen.;Matthew F Mart.;Hannah Kieffer.;David Krasinski.;Timothy D Girard.;Lauren E Ferrante.;Robert L Owens.;Ana Lucia Fuentes.;Nathan Brummel.;Carla M Sevin.;John P Kress.;Jaspal Singh.;Sukhvinder Nagi.;Kevin Shaw.;Edward Qian.;James C Jackson.;Christopher G Hughes.;Pratik Pandharipande.;Mayur Patel.;Tom Elasy.;E Wesley Ely.
来源: Chest. 2025年
Survivors of critical illness often experience new or worsening impairments in various domains of health after discharge, collectively referred to as post-intensive care syndrome (PICS). Although this condition is common, it remains unclear whether providers are communicating routinely about survivorship and PICS to patients and families and whether patients are remembering these conversations.
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